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Arthritis Research & Therapy 2009Osteoclast precursors arise from the CD14+ CD16- population in controls but details about cell surface marker expression and functional characteristics of these cells is...
Osteoclast precursors arise from the CD14+ CD16- population in controls but details about cell surface marker expression and functional characteristics of these cells is unknown, particularly in patients with inflammatory arthritis. In a recent issue of Arthritis, Research and Therapy, Lari and colleagues found that osteoclasts developed from a proliferative CD14+ CD16- subset in healthy controls. These cells took on the morphology of osteoclasts, expressed mRNA for osteoclast-related genes and excavated pits on bone wafers. These findings provide new insights into monocyte diversity and provide evidence that osteoclast precursors arise from a small proliferating monocyte population in controls. Additional studies are needed in patients with inflammatory arthritis.
Topics: Biomarkers; Blood Circulation; Cell Differentiation; Humans; Osteoclasts; Stem Cells
PubMed: 19591635
DOI: 10.1186/ar2707 -
Circulation Journal : Official Journal... Jul 2016
Topics: Blood Circulation; Humans; Periodicals as Topic
PubMed: 27439762
DOI: 10.1253/circj.CJ-66-0124 -
Medical Science Monitor : International... Jan 2018BACKGROUND It is unclear whether traditional application of Kinesio taping, which produces wrinkles in the skin, is effective for improving blood circulation. This study... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND It is unclear whether traditional application of Kinesio taping, which produces wrinkles in the skin, is effective for improving blood circulation. This study investigated local skin temperature changes after the application of an elastic therapeutic tape using convolution and non-convolution taping methods (CTM/NCTM). MATERIAL AND METHODS Twenty-eight pain-free men underwent CTM and NCTM randomly applied to the right and left sides of the lower back. Using infrared thermography, skin temperature was measured before, immediately after application, 5 min later, 15 min later, and after the removal of the tape. RESULTS Both CTM and NCTM showed a slight, but significant, decrease in skin temperature for up to 5 min. The skin temperature at 15 min and after the removal of the tape was not significantly different from the initial temperature for CTM and NCTM. There were also no significant differences in the skin temperatures between CTM and NCTM. CONCLUSIONS Our findings do not support a therapeutic effect of wrinkling the skin with elastic tape application as a technique to increase local blood flow.
Topics: Adult; Athletic Tape; Blood Circulation; Humans; Infrared Rays; Male; Skin; Skin Temperature; Thermography; Young Adult
PubMed: 29332101
DOI: 10.12659/msm.905708 -
BioMed Research International 2020Blood viscosity is one of the important parameters to characterize hemorheological properties of the human body. Its real-time and dynamic measurement has important...
Blood viscosity is one of the important parameters to characterize hemorheological properties of the human body. Its real-time and dynamic measurement has important physiological significance for studying the development and prevention of chronic diseases. This study researched noninvasive and personalized measurement of microvascular blood viscosity. In the microcirculation capillary network blood flow model, combined with pulse wave parameters, multiple regression analysis was used to fit the simulated radius of personalized physiological blood vessels to calculate the microvascular blood viscosity. The fitted value related to the simulated radius of the physiological blood vessel had a high correlation with the corresponding theoretically derived value (correlation coefficient: 0.904, ≤ 0.001). The calculated value of the microvascular blood viscosity had a certain correlation with the clinical whole blood viscosity at a low shear rate (correlation coefficient: 0.443, < 0.05). This algorithm could provide effective means for noninvasive and long-term individual monitoring and family health care.
Topics: Aged; Algorithms; Blood Circulation; Blood Viscosity; Humans; Male; Microcirculation
PubMed: 32953886
DOI: 10.1155/2020/7013212 -
Medecine Sciences : M/S Nov 2020In this first part we describe the different steps of the evolution of species and the circulatory modifications, which accompany it. From the open circulation in... (Review)
Review
In this first part we describe the different steps of the evolution of species and the circulatory modifications, which accompany it. From the open circulation in invertebrates, via the in-series closed circulation in fish, to the in-parallel closed circulation in mammals, the local ability to vasodilate in relation to the specific metabolic demand of territorial activity was the driving force for circulatory evolution. This capacity was achieved by the progressive muscularization of small arteries, generating frictional forces, which systemically determine high arterial pressure, and locally determine active vasodilation via the inhibition of vasomotor tone. This determinism differentially impacts the small resistance arteries, which generate blood pressure, and the large conductance arteries, which support the tensional stress generated by the blood pressure.
Topics: Adaptation, Biological; Animals; Biological Evolution; Biology; Blood Circulation; Earth, Planet; Genetic Speciation; History, 16th Century; History, 17th Century; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; Humans; Models, Biological; Phylogeny; Species Specificity
PubMed: 33151863
DOI: 10.1051/medsci/2020170 -
British Journal of Sports Medicine Mar 1993Massage has been a therapeutic modality in all cultures since early civilization and has had a long tradition of use in the sporting context. However, there has been a... (Review)
Review
Massage has been a therapeutic modality in all cultures since early civilization and has had a long tradition of use in the sporting context. However, there has been a paucity of scientific evidence of the physiological, psychological and therapeutic effects of commonly used massage techniques. This paper reviews the early and more recent studies on the effects of massage and also the more recent literature on its use on the sports person. Little agreement was found in English publications of the efficacy of massage and there were contradictory findings as to the optimum technique and length of time of application. It is clear that the role of massage - a time-consuming technique for a physiotherapist to perform - needs to be evaluated further in order to resolve some contentious issues arising about this mode of treatment and to justify its use.
Topics: Animals; Blood Circulation; Humans; Massage; Movement; Muscles; Sports; Time Factors
PubMed: 8457807
DOI: 10.1136/bjsm.27.1.28 -
Nature Reviews. Cancer Jul 2012Recent technological advances that have enabled the measurement of circulating tumour cells (CTCs) in patients have spurred interest in the circulatory phase of...
Recent technological advances that have enabled the measurement of circulating tumour cells (CTCs) in patients have spurred interest in the circulatory phase of metastasis. Techniques that do not solely rely on a blood sample allow substantial biological interrogation beyond simply counting CTCs.
Topics: Blood Circulation; Humans; Neoplasm Metastasis; Neoplastic Cells, Circulating
PubMed: 22912952
DOI: 10.1038/nrc3287 -
British Medical Journal May 1952
Topics: Blood Circulation; Epinephrine; Humans; Norepinephrine
PubMed: 14925344
DOI: 10.1136/bmj.1.4766.1003 -
American Journal of Physiology. Heart... Aug 2006We present an in vivo method for analyzing the distribution kinetics of physiological markers into their respective distribution volumes utilizing information provided...
We present an in vivo method for analyzing the distribution kinetics of physiological markers into their respective distribution volumes utilizing information provided by the relative dispersion of transit times. Arterial concentration-time curves of markers of the vascular space [indocyanine green (ICG)], extracellular fluid (inulin), and total body water (antipyrine) measured in awake dogs under control conditions and during phenylephrine or isoproterenol infusion were analyzed by a recirculatory model to estimate the relative dispersions of transit times across the systemic and pulmonary circulation. The transit time dispersion in the systemic circulation was used to calculate the whole body distribution clearance, and an interpretation is given in terms of a lumped organ model of blood-tissue exchange. As predicted by theory, this relative dispersion increased linearly with cardiac output, with a slope that was inversely related to solute diffusivity. The relative dispersion of the flow-limited indicator antipyrine exceeded that of ICG (as a measure of intravascular mixing) only slightly and was consistent with a diffusional equilibration time in the extravascular space of approximately 10 min, except during phenylephrine infusion, which led to an anomalously high relative dispersion. A change in cardiac output did not alter the heterogeneity of capillary transit times of ICG. The results support the view that the relative dispersions of transit times in the systemic and pulmonary circulation estimated from solute disposition data in vivo are useful measures of whole body distribution kinetics of indicators and endogenous substances. This is the first model that explains the effect of flow and capillary permeability on whole body distribution of solutes without assuming well-mixed compartments.
Topics: Adrenergic beta-Agonists; Algorithms; Animals; Antipyrine; Blood Circulation; Cardiac Output; Diffusion; Dogs; Hindlimb; Indocyanine Green; Insulin; Isoproterenol; Male; Models, Biological; Models, Statistical; Phenylephrine; Pulmonary Circulation; Regional Blood Flow; Vasoconstrictor Agents
PubMed: 16501020
DOI: 10.1152/ajpheart.01052.2005 -
Cardiologia (Rome, Italy) Sep 1999Hemodynamics stands on three main physical principles: the hydrostatic pressure, firstly described by Stevino, the viscous flow pressure, described by Poiseuille and the... (Review)
Review
Hemodynamics stands on three main physical principles: the hydrostatic pressure, firstly described by Stevino, the viscous flow pressure, described by Poiseuille and the total hydraulic energy, or Bernoulli's equation. However, neither of these physical principles gives a comprehensive description of the single pressure measurement in the cardiovascular system. Hence, all these principles should be used together to fully describe the physical forces acting in the circulation of blood. Experiments that measured the hydrostatic pressure in the jugular vein of the giraffe have shown that a few guidelines need to be followed to measure it correctly. Following these guidelines, it can be seen that hydrostatic and viscous flow pressures are strictly related to one another, and that this relationship is described in mathematical terms. In addition, it has been shown that hydrostatic and viscous pressures should be included in Bernoulli's principle, to give the combined Bernoulli-Poiseuille equation. This unified principle is helpful not only to measure correctly the pressure with a catheter connected to a pressure transducer, but also to give to the pressure measured in a patient with the mercury manometer, a strong connection with the description of the pressure as a physical force acting inside the circulation. In addition it provides a comprehensive view of the cardiovascular system as a closed hydrodynamic system, in which the heart is a pump, that does not normally work to overcome the force of gravity. The question at this point is: are there any pathophysiological conditions in which the heart needs to be confronted with the sudden appearance of the force of gravity inside the cardiovascular system?
Topics: Animals; Artiodactyla; Biophysical Phenomena; Biophysics; Blood Circulation; Gravitation; Hemodynamics; Mathematics
PubMed: 10609386
DOI: No ID Found