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Asia-Pacific Journal of Ophthalmology... Dec 2020Corneal grafting is one of the most common forms of human tissue transplantation. The corneal stroma is responsible for many characteristics of the cornea. For these... (Review)
Review
Corneal grafting is one of the most common forms of human tissue transplantation. The corneal stroma is responsible for many characteristics of the cornea. For these reasons, an important volume of research has been made to replicate the corneal stroma in the laboratory to find an alternative to classical corneal transplantation techniques.There is an increasing interest today in cell therapy of the corneal stroma using induced pluripotent stem cells or mesenchymal stem cells since these cells have shown to be capable of producing new collagen within the host stroma and even to improve its transparency.The first clinical experiment on corneal stroma regeneration in advanced keratoconus cases has been reported and included. Fourteen patients were randomized and enrolled into 3 experimental groups: (1) patients underwent implantation of autologous adipose-derived adult stem cells alone, (2) patients received decellularized donor corneal stroma laminas, and (3) patients received implantation of recellularized donor laminas with adipose-derived adult stem cells. Clinical improvement was detected with all cases in their visual, pachymetric, and topographic parameters of the operated corneas.Other recent studies have used allogenic SMILE implantation lenticule corneal inlays, showing also an improvement in different visual, topographic, and keratometric parameters.In the present report, we try to summarize the available preclinical and clinical evidence about the emerging topic of corneal stroma regeneration.
Topics: Corneal Stroma; Corneal Topography; Corneal Transplantation; Humans; Keratoconus; Tomography, Optical Coherence; Visual Acuity
PubMed: 33181549
DOI: 10.1097/APO.0000000000000337 -
Journal of Indian Prosthodontic Society 2020The aim of this meta analysis was to evaluate the influence of the processing method on the marginal and internal gaps of lithium disilicate inlays/onlays. (Review)
Review
AIM
The aim of this meta analysis was to evaluate the influence of the processing method on the marginal and internal gaps of lithium disilicate inlays/onlays.
SETTINGS AND DESIGN
A systematic literature review was conducted using the PubMed/Medline, Embase, Scopus, and Cochrane Library databases. This review was registered on the PROSPERO platform.
MATERIALS AND METHODS
The studies were selected according to the marginal and internal gaps of two different fabrication methods for lithium disilicate (milled and pressed).
STATISTICAL ANALYSIS USED
The meta analysis was performed based on the Mantel-Haenszel and inverse variance methods, using the random effects model and a 95% confidence interval.
RESULTS
From all databases, 127 studies were identified. Four in vitro studies were included in the qualitative analysis and three in the meta analysis. Moreover, 197 restorations were evaluated (103 pressed and 94 milled). During the evaluation of only the internal gap, there was a statistically significant difference favoring the pressed technique ( = 0.002). There was no statistically significant difference in the analyses of the marginal gap ( = 0.530) and the total gap ( = 0.450).
CONCLUSION
Both the techniques provided acceptable marginal and total gaps, although the pressed technique revealed a more favorable internal adaptation than the milled onlays/inlays.
PubMed: 33487960
DOI: 10.4103/jips.jips_112_20 -
Australian Dental Journal Sep 1999The availability of improved ceramic materials, bonding techniques, new technology and issues of amalgam safety have led to a revival of interest in ceramic inlays in... (Review)
Review
The availability of improved ceramic materials, bonding techniques, new technology and issues of amalgam safety have led to a revival of interest in ceramic inlays in dentistry over the past ten years. Clinical studies have been carried out during this time using various evaluation techniques to assess the clinical performance of these restorations. In this paper, recent clinical studies are examined and a review of the current state of knowledge regarding the clinical performance and survival statistics of ceramic inlays is presented. The major problems associated with ceramic inlay therapy appear to be fracture, hypersensitivity, degree of fit, maintenance of marginal integrity, microleakage, bond failures and cement wear. Other areas which also affect the clinical performance of ceramic inlays are ceramic wear, opposing tooth wear, plaque accumulation, gingivitis, secondary caries, colour stability, anatomic form and radiopacity. Recommendations based on the findings of clinical studies are also presented and whilst no specific material or technique has been shown to be clearly superior, certain principles which predispose to success can be identified. When compared with other forms of aesthetic intracoronal restorations, ceramic inlays perform well. However, their high cost and extreme technique sensitivity would appear to restrict their use to certain limited clinical situations.
Topics: Ceramics; Clinical Trials as Topic; Dental Bonding; Dental Cements; Dental Leakage; Dental Restoration Failure; Dental Restoration Wear; Humans; Inlays
PubMed: 10592560
DOI: 10.1111/j.1834-7819.1999.tb00217.x -
Medical Science Monitor : International... Jun 2018BACKGROUND The aim of this study was to investigate and compare the load-bearing capacities of three-unit direct resin-bonded fiber-reinforced composite fixed dental... (Comparative Study)
Comparative Study
BACKGROUND The aim of this study was to investigate and compare the load-bearing capacities of three-unit direct resin-bonded fiber-reinforced composite fixed dental prosthesis with different framework designs. MATERIAL AND METHODS Sixty mandibular premolar and molar teeth without caries were collected and direct glass fiber-resin fixed FDPs were divided into 6 groups (n=10). Each group was restored via direct technique with different designs. In Group 1, the inlay-retained bridges formed 2 unidirectional FRC frameworks and pontic-reinforced transversal FRC. In Group 2, the inlay-retained bridges were supported by unidirectional lingual and occlusal FRC frameworks. Group 3, had buccal and lingual unidirectional FRC frameworks without the inlay cavities. Group 4 had reinforced inlay cavities and buccal-lingual FRC with unidirectional FRC frameworks. Group 5, had a circular form of fiber reinforcement around cusps in addition to buccal-lingual FRC frameworks. Group 6 had a circular form of fiber reinforcement around cusps with 2 bidirectional FRC frameworks into inlay cavities. All groups were loaded until final fracture using a universal testing machine at a crosshead speed of 1 mm/min. RESULTS Mean values of the groups were determined with ANOVA and Tukey HSD. When all data were evaluated, Group 6 had the highest load-bearing capacities and revealed significant differences from Group 3 and Group 4. Group 6 had the highest strain (p>0.05). When the fracture patterns were investigated, Group 6 had the durability to sustain fracture propagation within the restoration. CONCLUSIONS The efficiency of fiber reinforcement of the restorations alters not only the amount of fiber, but also the design of the restoration with fibers.
Topics: Dental Cements; Dental Materials; Dental Prosthesis Design; Dental Stress Analysis; Humans; Weight-Bearing
PubMed: 29950555
DOI: 10.12659/MSM.909271 -
The Dental Register Aug 1907
PubMed: 33701725
DOI: No ID Found -
The Dental Register May 1908
PubMed: 33702288
DOI: No ID Found -
The Dental Register Oct 1906
PubMed: 33702020
DOI: No ID Found -
The American Journal of Dental Science Apr 1906
PubMed: 30751094
DOI: No ID Found -
The American Journal of Dental Science May 1899
PubMed: 30750152
DOI: No ID Found -
The Dental Register Jun 1897
PubMed: 33700681
DOI: No ID Found