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BMC Geriatrics Apr 2023The association between sensory impairment including vision impairment (VI), hearing impairment (HI), dual impairment (DI) and the functional limitations of SCD...
BACKGROUND
The association between sensory impairment including vision impairment (VI), hearing impairment (HI), dual impairment (DI) and the functional limitations of SCD (SCD-related FL) are still unclear in middle-aged and older people.
METHODS
162,083 participants from BRFSS in 2019 to 2020 was used in this cross-sectional study. After adjusting the weights, multiple logistic regression was used to study the relationship between sensory impairment and SCD or SCD-related FL. In addition, we performed subgroup analysis on the basis of interaction between sensory impairment and covariates.
RESULTS
Participants who reported sensory impairment were more likely to report SCD or SCD-related FL compared to those without sensory impairment (pā<ā0.001). The association between dual impairment and SCD-related FL was the strongest, the adjusted odds ratios (aORs) and 95% confidence interval (95% CI) were [HI, 2.88 (2.41, 3.43); VI, 3.15(2.61, 3.81); DI, 6.78(5.43, 8.47)] respectively. In addition, subgroup analysis showed that men with sensory impairment were more likely to report SCD-related FL than women, the aORs and 95% CI were [HI, 3.15(2.48, 3.99) vs2.69(2.09, 3.46); VI,3.67(2.79, 4.83) vs. 2.86(2.22, 3.70); DI, 9.07(6.67, 12.35) vs. 5.03(3.72, 6.81)] respectively. The subject of married with dual impairment had a stronger association with SCD-related FL than unmarried subjects the aOR and 95% CI was [9.58(6.69, 13.71) vs. 5.33(4.14, 6.87)].
CONCLUSIONS
Sensory impairment was strongly associated with SCD and SCD-related FL. Individuals with dual impairment had the greatest possibility to reported SCD-related FL, and the association was stronger for men or married subjects than other subjects.
Topics: Male; Humans; Female; Middle Aged; Aged; Cross-Sectional Studies; Vision Disorders; Hearing Loss; Cognitive Dysfunction; Disabled Persons
PubMed: 37060058
DOI: 10.1186/s12877-023-03950-x -
International Journal of Oral and... Oct 2022The aim of this systematic review was to review the literature on hearing impairment and ear anomalies in patients with craniofacial microsomia and to determine their... (Review)
Review
The aim of this systematic review was to review the literature on hearing impairment and ear anomalies in patients with craniofacial microsomia and to determine their prevalence. Sixty-two records including 5122 patients were included. Ear anomalies were present in 52-100% of patients. The most reported external ear malformations were microtia, pre-auricular tags, and atresia of the external auditory canal. Ossicular anomalies were the most reported middle ear malformations, whereas the most reported inner ear malformations included oval window anomalies, cochlear anomalies, and anomalies of the semicircular canals. Hearing loss in general was reported in 29-100% of patients, which comprised conductive hearing loss, mixed hearing loss, and sensorineural hearing loss. Between 21% and 51% of patients used hearing aids, and 58% underwent a surgical intervention to improve hearing. The relationship between different phenotypes of craniofacial microsomia and the type and severity of hearing loss is mostly unclear. In conclusion, the high prevalence of ear and hearing anomalies in patients with craniofacial microsomia underlines the importance of audiological screening in order to facilitate individual treatment.
Topics: Goldenhar Syndrome; Hearing Loss; Hearing Loss, Conductive; Hearing Loss, Sensorineural; Humans; Phenotype; Retrospective Studies
PubMed: 35125269
DOI: 10.1016/j.ijom.2022.01.005 -
Tropical Medicine & International... Feb 2016To systematically assess the data on the prevalence and causes of hearing impairment in Africa. (Review)
Review
OBJECTIVE
To systematically assess the data on the prevalence and causes of hearing impairment in Africa.
METHODS
Systematic review on the prevalence and causes of hearing loss in Africa. We undertook a literature search of seven electronic databases (EMBASE, PubMed, Medline, Global Health, Web of Knowledge, Academic Search Complete and Africa Wide Information) and manually searched bibliographies of included articles. The search was restricted to population-based studies on hearing impairment in Africa. Data were extracted using a standard protocol.
RESULTS
We identified 232 articles and included 28 articles in the final analysis. The most common cut-offs used for hearing impairment were 25 and 30 dB HL, but this ranged between 15 and 40 dB HL. For a cut-off of 25 dB, the median was 7.7% for the children- or school-based studies and 17% for population-based studies. For a cut-off of 30 dB HL, the median was 6.6% for the children or school-based studies and 31% for population-based studies. In schools for the deaf, the most common cause of hearing impairment was cryptogenic deafness (50%) followed by infectious causes (43%). In mainstream schools and general population, the most common cause of hearing impairment was middle ear disease (36%), followed by undetermined causes (35%) and cerumen impaction (24%).
CONCLUSION
There are very few population-based studies available to estimate the prevalence of hearing impairment in Africa. Those studies that are available use different cut-offs, making comparison difficult. However, the evidence suggests that the prevalence of hearing impairment is high and that much of it is avoidable or treatable.
Topics: Africa; Hearing Loss; Humans; Prevalence
PubMed: 26584722
DOI: 10.1111/tmi.12640 -
Eastern Mediterranean Health Journal =... Jan 2023Hearing impairment and its consequences in children are often worsened by late identification in Pakistan. Deep-rooted cultural beliefs make some parents reluctant to...
BACKGROUND
Hearing impairment and its consequences in children are often worsened by late identification in Pakistan. Deep-rooted cultural beliefs make some parents reluctant to seek clinical treatment, making adaptable solutions that traverse levels of socio-ecological model necessary.
AIMS
To determine the impact of hearing impairment on children's participation in social activities, and the financial burden on their parents.
METHODS
This cross-sectional study included 377 parents of children with hearing impairment. The sample was recruited from special education schools and hospitals in Islamabad and Lahore, Pakistan, from November 2015 to April 2016. A 15-item structured questionnaire was used for data collection. SPSS version 21 was used for statistical analysis.
RESULTS
Among children with hearing impairment, 47.5% faced moderate challenges in joining social activities, and 26.0% faced severe challenges. There was a significant positive correlation between the severity of hearing impairment, the person who suspected hearing impairment, age of detection of hearing impairment, and time of referral. Children with hearing impairment caused moderate financial strain on 39.0% of parents and mild strain on 26.8%.
CONCLUSION
Hearing impairment can significantly impact children's participation in social activities and cause financial burdens on their parents.
Topics: Humans; Child; Pakistan; Cross-Sectional Studies; Parents; Hearing Loss; Surveys and Questionnaires
PubMed: 36710612
DOI: 10.26719/emhj.23.012 -
Journal of Ayub Medical College,... 2017Hereditary hearing impairment is heterogeneous type of disorder which can be caused due to environmental as well as genetical factors. Two distinct types of hereditary... (Review)
Review
Hereditary hearing impairment is heterogeneous type of disorder which can be caused due to environmental as well as genetical factors. Two distinct types of hereditary hearing loss are syndromic or non-syndromic. Non-syndromic hearing loss is further categorized as autosomal recessive, autosomal dominant, X-linked and mitochondrial deafness. Autosomal recessive occurs more frequently as compared to autosomal dominant. Mutations in various genes are responsible for hereditary hearing impairment. To date, about 99 autosomal recessives and 67 autosomal dominant genes for deafness have been discovered. Some of important genes include GJB2, JGB6, GJB3 which encodes gap junction proteins, MYO7A, MYO15A encodes myosine proteins, OTOF encodes otoferlin, and SLC26A4 encodes anion exchanger protein. Up till now, the mutation in GJB2 gene occurs more frequently in different population of the world and cause autosomal recessive hearing impairment. The purpose of this review article was to explore the mutation and function of those muted genes which encode different type of protein and responsible either for autosomal recessive or autosomal dominant hearing impairment.
Topics: Hearing Loss; Humans
PubMed: 29331002
DOI: No ID Found -
Ear and Hearing 2017To undertake a systematic review of available evidence on the effect of hearing impairment and hearing aid amplification on listening effort. Two research questions were... (Review)
Review
OBJECTIVES
To undertake a systematic review of available evidence on the effect of hearing impairment and hearing aid amplification on listening effort. Two research questions were addressed: Q1) does hearing impairment affect listening effort? and Q2) can hearing aid amplification affect listening effort during speech comprehension?
DESIGN
English language articles were identified through systematic searches in PubMed, EMBASE, Cinahl, the Cochrane Library, and PsycINFO from inception to August 2014. References of eligible studies were checked. The Population, Intervention, Control, Outcomes, and Study design strategy was used to create inclusion criteria for relevance. It was not feasible to apply a meta-analysis of the results from comparable studies. For the articles identified as relevant, a quality rating, based on the 2011 Grading of Recommendations Assessment, Development, and Evaluation Working Group guidelines, was carried out to judge the reliability and confidence of the estimated effects.
RESULTS
The primary search produced 7017 unique hits using the keywords: hearing aids OR hearing impairment AND listening effort OR perceptual effort OR ease of listening. Of these, 41 articles fulfilled the Population, Intervention, Control, Outcomes, and Study design selection criteria of: experimental work on hearing impairment OR hearing aid technologies AND listening effort OR fatigue during speech perception. The methods applied in those articles were categorized into subjective, behavioral, and physiological assessment of listening effort. For each study, the statistical analysis addressing research question Q1 and/or Q2 was extracted. In seven articles more than one measure of listening effort was provided. Evidence relating to Q1 was provided by 21 articles that reported 41 relevant findings. Evidence relating to Q2 was provided by 27 articles that reported 56 relevant findings. The quality of evidence on both research questions (Q1 and Q2) was very low, according to the Grading of Recommendations Assessment, Development, and Evaluation Working Group guidelines. We tested the statistical evidence across studies with nonparametric tests. The testing revealed only one consistent effect across studies, namely that listening effort was higher for hearing-impaired listeners compared with normal-hearing listeners (Q1) as measured by electroencephalographic measures. For all other studies, the evidence across studies failed to reveal consistent effects on listening effort.
CONCLUSION
In summary, we could only identify scientific evidence from physiological measurement methods, suggesting that hearing impairment increases listening effort during speech perception (Q1). There was no scientific, finding across studies indicating that hearing aid amplification decreases listening effort (Q2). In general, there were large differences in the study population, the control groups and conditions, and the outcome measures applied between the studies included in this review. The results of this review indicate that published listening effort studies lack consistency, lack standardization across studies, and have insufficient statistical power. The findings underline the need for a common conceptual framework for listening effort to address the current shortcomings.
Topics: Auditory Fatigue; Auditory Perception; Hearing Aids; Hearing Loss; Humans
PubMed: 28234670
DOI: 10.1097/AUD.0000000000000396 -
Ear and Hearing 2017Hearing loss (HL) is a common sensory impairment in humans, with significant economic and social impacts. With nearly 20% of the world's population, China has focused on... (Review)
Review
Hearing loss (HL) is a common sensory impairment in humans, with significant economic and social impacts. With nearly 20% of the world's population, China has focused on economic development and health awareness to improve the care for its hearing-impaired population. Recently, the Chinese government has initiated national programs such as the China Disabled Persons Federation to fund prevention, treatment, and rehabilitation of hearing impairment. Newborn hearing screening and auditory rehabilitation programs in China have expanded exponentially with government support. While facing many challenges and overcoming obstacles, cochlear implantation (CI) programs in China have also experienced considerable growth. This review discusses the implementation of CI programs for HL in China and presents current HL data including epidemiology, newborn hearing screening, and determination of genetic etiologies. Sharing the experience in Chinese auditory rehabilitation and CI programs will shine a light on the developmental pathway of healthcare infrastructure to meet emerging needs of the hearing-impaired population in other developing countries.
Topics: China; Cochlear Implantation; Cochlear Implants; Correction of Hearing Impairment; Hearing Loss; Hearing Tests; Humans; Infant, Newborn; Neonatal Screening; Program Development
PubMed: 28471842
DOI: 10.1097/AUD.0000000000000441 -
EMBO Molecular Medicine Aug 2022Hearing impairment, the most prevalent sensory deficit, affects more than 466 million people worldwide (WHO). We presently lack causative treatment for the most common... (Review)
Review
Hearing impairment, the most prevalent sensory deficit, affects more than 466 million people worldwide (WHO). We presently lack causative treatment for the most common form, sensorineural hearing impairment; hearing aids and cochlear implants (CI) remain the only means of hearing restoration. We engaged with CI users to learn about their expectations and their willingness to collaborate with health care professionals on establishing novel therapies. We summarize upcoming CI innovations, gene therapies, and regenerative approaches and evaluate the chances for clinical translation of these novel strategies. We conclude that there remains an unmet medical need for improving hearing restoration and that we are likely to witness the clinical translation of gene therapy and major CI innovations within this decade.
Topics: Cochlear Implantation; Cochlear Implants; Hearing; Hearing Aids; Hearing Loss; Hearing Loss, Sensorineural; Humans
PubMed: 35833443
DOI: 10.15252/emmm.202215798 -
Australian Family Physician Jun 2016Hearing loss affects one in six Australians and has an extensive psychosocial impact on patients. Hearing technology has made marked improvements over the past 30 years... (Review)
Review
BACKGROUND
Hearing loss affects one in six Australians and has an extensive psychosocial impact on patients. Hearing technology has made marked improvements over the past 30 years and device options for patients with hearing impairment are continuously emerging.
OBJECTIVE
This article reviews currently available implantable hearing devices and their utility in certain patient populations. It also high-lights the patient characteristics that general practitioners (GPs) can use in identifying a patient who may benefit from referral to an implant program.
DISCUSSION
The prevalence of hearing loss is increasing. The available options for hearing rehabilitation are continuously expanding, with improvements in technology, design and patient outcomes. In Australia, available implantable hearing devices include percutaneous and transcutaneous bone conducting aids, and cochlear implants. Complication rates continue to decrease as advances in operative techniques, and device design and function allow for expansion of device indications among the patient population.
Topics: Cochlear Implants; General Practice; Hearing Loss; Humans
PubMed: 27622224
DOI: No ID Found -
Genes Dec 2020We have investigated the main genetic causes for non-syndromic hearing impairment (NSHI) in the hearing impairment individuals from the North-Eastern Romania and... (Review)
Review
BACKGROUND
We have investigated the main genetic causes for non-syndromic hearing impairment (NSHI) in the hearing impairment individuals from the North-Eastern Romania and proposed a cost-effective diagnosis protocol.
METHODS
MLPA followed by Sanger Sequencing were used for all 291 patients included in this study.
RESULTS
MLPA revealed abnormal results in 141 cases (48.45%): 57 (40.5%) were c.35delG homozygous, 26 (18.44%) were c.35delG heterozygous, 14 (9.93%) were compound heterozygous and 16 (11.35%) had other types of variants. The entire coding region of was sequenced and out of 150 patients with normal results at MLPA, 29.33% had abnormal results: variants in heterozygous state: c.71G>A (28%), c.457G>A (20%), c.269T>C (12%), c.109G>A (12%), c.100A>T (12%), c.551G>C (8%). Out of 26 patients with c.35delG in heterozygous state, 38.46% were in fact compound heterozygous.
CONCLUSIONS
We identified two variants: c.109G>A and c.100A>T that have not been reported in any study from Romania. MLPA is an inexpensive, rapid and reliable technique that could be a cost-effective diagnosis method, useful for patients with hearing impairment. It can be adaptable for the mutation spectrum in every population and followed by Sanger sequencing can provide a genetic diagnosis for patients with different degrees of hearing impairment.
Topics: Adolescent; Adult; Audiometry; Child; Child, Preschool; Connexin 26; Cost-Benefit Analysis; Female; Genetic Association Studies; Genotype; Hearing Loss; Hearing Loss, Bilateral; Humans; Infant; Male; Mass Screening; Membrane Proteins; Middle Aged; Multiplex Polymerase Chain Reaction; Point Mutation; Romania; Sequence Analysis, DNA; Young Adult
PubMed: 33333757
DOI: 10.3390/genes11121506