-
Oncology (Williston Park, N.Y.) Apr 2015
PubMed: 25930896
DOI: No ID Found -
British Journal of Cancer Apr 1984The true survival rates for the various forms of childhood cancer are best determined from a population-based study rather than from the results of clinical trials....
The true survival rates for the various forms of childhood cancer are best determined from a population-based study rather than from the results of clinical trials. Population-based survival rates have been calculated for four periods between 1956 and 1980 in Queensland. There was a significant improvement in survival for children who developed cancer after 1973 compared with those diagnosed before this date. There has however been no significant improvement in the survival rate for childhood cancer overall, or for acute lymphoblastic leukaemia since 1973. Over the 25 year period significant trends in survival rates were seen in acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin's disease, Wilms' tumour, medulloblastoma, and retinoblastoma. No such trend was seen for acute non-lymphoblastic leukaemia, neuroblastoma, rhabdomyosarcoma, juvenile or anaplastic astrocytoma, brain stem glioma, histiocytosis X, or bone tumours. There is a need for continuing research into better methods of treatment of childhood cancer.
Topics: Adolescent; Australia; Child; Child, Preschool; Follow-Up Studies; Humans; Infant; Leukemia, Lymphoid; Neoplasms; Time Factors
PubMed: 6585217
DOI: 10.1038/bjc.1984.79 -
BMJ Case Reports Jun 2015We present a case of a 19-year-old man with cervical lymphadenopathy diagnosed with classical Hodgkin's lymphoma 9 years after gross total resection of a third...
We present a case of a 19-year-old man with cervical lymphadenopathy diagnosed with classical Hodgkin's lymphoma 9 years after gross total resection of a third ventricular juvenile pilocytic astrocytoma (JPA). Chemotherapy or radiation therapy was not a part of his initial JPA treatment. Owing to his two primary neoplasms, genetic testing was performed, which revealed heterozygous polymorphisms of unknown significance for CDH1 and p53, and negative BRAF mutation analysis. Our case reports development of classical Hodgkin's lymphoma after JPA in the absence of antecedent radiation and/or chemotherapy, and identifiable genetic predisposition.
Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Genetic Predisposition to Disease; Genetic Testing; Hodgkin Disease; Humans; Male; Polymorphism, Genetic; Young Adult
PubMed: 26113587
DOI: 10.1136/bcr-2015-209343 -
Journal of Clinical Pathology Jul 1964One hundred and fifty-five tumours of the central nervous system which occurred in children in the north west of England during a period of nine years are analysed from...
One hundred and fifty-five tumours of the central nervous system which occurred in children in the north west of England during a period of nine years are analysed from a pathological point of view. It is probable that these represent over 90% of all such tumours occurring in the region at that time and that the relative incidence of various tumour types is, therefore, a true one: just over a fifth (35) were medulloblastomas; just under a fifth (29) were juvenile astrocytomas; a similar group (33) were of the adult astrocytic type; there were 24 ependymomas and 34 in miscellaneous minor groups.
Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; England; Ependymoma; Humans; Infant; Lipoma; Medulloblastoma; Melanoma; Meningeal Neoplasms; Meningioma; Mesenchymoma; Neoplasms; Pathology; Pinealoma; Pituitary Neoplasms; Teratoma
PubMed: 14198334
DOI: 10.1136/jcp.17.4.418