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Medical Science Monitor : International... Sep 2018BACKGROUND Previous studies have shown that differences in marital status contribute to different prognoses for certain cancers, but the relationship between marital...
BACKGROUND Previous studies have shown that differences in marital status contribute to different prognoses for certain cancers, but the relationship between marital status and the prognosis of chondrosarcoma has not been reported previously. MATERIAL AND METHODS In this study, we selected 4502 eligible cases through the Surveillance, Epidemiology, and End Results (SEER) database from 1977 to 2014 to analyze the impact of marital status on chondrosarcoma cancer-specific survival (CSS) by Kaplan-Meier method and Cox regression model. RESULTS The sex, age, histotype, pathological grade, tumor location, tumor size, SEER stage, socioeconomic status, marital status, and treatment were identified as independent prognostic factors for chondrosarcoma CSS. Widowed patients presented the worst CSS compared with their married, divorced, and single counterparts (P<0.001). Subgroup analyses showed widowed patients also had a significantly higher risk of cancer-specific mortality compared with married patients in localized stage (HR: 1.971, 95% CI: 1.298-2.994, P=0.001), regional stage (HR: 1.535, 95% CI: 1.094-2.154, P=0.013), low pathological grade (HR: 1.866, 95% CI: 1.332-2.613, P<0.001), and high pathological grade (HR: 1.662, 95% CI: 1.139-2.426, P=0.008). CONCLUSIONS Marital status was first identified as an independent prognostic factor for chondrosarcoma CSS, and widowhood was always associated with a high risk of cancer-specific mortality. It is necessary to provide timely psychological treatment for widowed patients in clinical practice, which can improve the survival of chondrosarcoma patients.
Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Chondrosarcoma; Female; Humans; Kaplan-Meier Estimate; Male; Marital Status; Middle Aged; Prognosis; Regression Analysis; Retrospective Studies; Risk Factors; SEER Program; Survival Analysis; United States; Widowhood
PubMed: 30235178
DOI: 10.12659/MSM.911673 -
Cancer Medicine Oct 2021Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of...
BACKGROUND
Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet.
METHODS
A total of 3375 eligible cases diagnosed from 2004 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Association of marital status with stage and survival in patients with MF was analyzed.
RESULTS
Married patients were more likely to be diagnosed at T1 stage (p = 0.041). And married patients were less likely to present with lymph node involvement (p = 0.007). More favorable overall survival (p < 0.001) and cancer-specific survival (p < 0.001) were demonstrated in married patients as compared with divorced patients or widowed patients. A clinically feasible prognostic model including marital status, age, sex, race, and stage at presentation was constructed.
CONCLUSION
Married marital status was associated with earlier stage at diagnosis and longer survival compared with divorced or widowed marital status in patients with MF.
Topics: Aged; Female; Humans; Male; Marital Status; Middle Aged; Mycosis Fungoides; Neoplasm Staging; Prognosis; SEER Program; Survival Analysis
PubMed: 34480528
DOI: 10.1002/cam4.4232 -
The Journals of Gerontology. Series B,... Aug 2018Our study compares two types of later life marital dissolution that occur after age 50-divorce and widowhood-and their associations with repartnership status (i.e.,...
OBJECTIVES
Our study compares two types of later life marital dissolution that occur after age 50-divorce and widowhood-and their associations with repartnership status (i.e., remarried, cohabiting, or unpartnered).
METHOD
We used data from the Health and Retirement Study to provide a portrait of later life divorce and widowhood for women and men. Next, we tested whether marital dissolution type is related to women's and men's repartnered status, distinguishing among remarrieds, cohabitors, and unpartnereds, net of key sociodemographic indicators.
RESULTS
Divorcees are more often repartnered through either remarriage or cohabitation than are widoweds. This gap persists among women net of an array of sociodemographic factors. For men, the differential is reduced to nonsignificance with the inclusion of these factors.
DISCUSSION
Later life marital dissolution increasingly occurs through divorce rather than widowhood, and divorce is more often followed by repartnership. The results from this study suggest that gerontological research should not solely focus on widowhood but also should pay attention to divorce and repartnering during later life.
Topics: Age Factors; Aged; Aged, 80 and over; Divorce; Female; Humans; Longitudinal Studies; Male; Marriage; Middle Aged; Socioeconomic Factors; Spouses; United States; Widowhood
PubMed: 27131167
DOI: 10.1093/geronb/gbw051 -
Scientific Reports Jan 2021Marital status has long been recognized as an important prognostic factor for many cancers, however its' prognostic effect for patients with laryngeal cancer has not...
Marital status has long been recognized as an important prognostic factor for many cancers, however its' prognostic effect for patients with laryngeal cancer has not been fully examined. We retrospectively analyzed 8834 laryngeal cancer patients in the Surveillance Epidemiology and End Results database from 2004 to 2010. Patients were divided into four groups: married, widowed, single, and divorced/separated. The difference in overall survival (OS) and cancer-specific survival (CSS) of the various marital subgroups were calculated using the Kaplan-Meier curve. Multivariate Cox regression analysis screened for independent prognostic factors. Propensity score matching (PSM) was also conducted to minimize selection bias. We included 8834 eligible patients (4817 married, 894 widowed, 1732 single and 1391 divorced/separated) with laryngeal cancer. The 5-year OS and CSS of married, widowed, single, and separated/divorced patients were examined. Univariate and multivariate analyses found marital status to be an independent predictor of survival. Subgroup survival analysis showed that the OS and CSS rates in widowed patients were always the lowest in the various American Joint Committee on Cancer stages, irrespective of sex. Widowed patients demonstrated worse OS and CSS in the 1:1 matched group analysis. Among patients with laryngeal cancer, widowed patients represented the highest-risk group, with the lowest OS and CSS.
Topics: Aged; China; Female; Humans; Laryngeal Neoplasms; Male; Marital Status; Prognosis; Retrospective Studies; Risk Factors; SEER Program; Survival Rate
PubMed: 33436991
DOI: 10.1038/s41598-020-80698-z -
Journal of Family Psychology : JFP :... Apr 2015Previous research has shown marital status and marital quality are consistent predictors of health outcomes, including cardiovascular disease and mortality. To better...
Previous research has shown marital status and marital quality are consistent predictors of health outcomes, including cardiovascular disease and mortality. To better understand the relationship among marital status, marital quality, and cardiovascular health, we examined how marital status and marital quality were associated with an early indicator of deteriorating cardiovascular health, high-frequency heart rate variability (HF-HRV). This study uses data from the National Survey of Midlife in the United States (MIDUS) Biomarker Substudy (N = 907) to examine differences in HF-HRV by traditional marital status categories (married, divorced, widowed, and never married) as well as further differentiating between the continuously married and remarried. In addition, links were also examined between HF-HRV and changes in marital quality (marital satisfaction, support, strain) among individuals in long-term marriages. No significant differences in HF-HRV were observed between married persons and those widowed, divorced, and never married. However, continuously married individuals had higher HF-HRV than remarried adults. Increases in marital satisfaction and support over 10 years were associated with higher HF-HRV, whereas increased marital strain over 10 years was associated with lower HF-HRV. Higher HF-HRV among the continuously married compared with the remarried suggests that previous marital disruptions may have lasting effects on cardiovascular health or that there may be other differences between the remarried versus those who remain married to the same person. Associations between marital quality and HF-HRV suggest that variations in the quality of one's marriage may affect cardiovascular health.
Topics: Adult; Aged; Cohort Studies; Female; Health Surveys; Heart Rate; Humans; Male; Marital Status; Middle Aged; Personal Satisfaction; Spouses; United States
PubMed: 25844496
DOI: 10.1037/fam0000068 -
Fertility and Sterility Jun 2015To examine female and male sterilization patterns in the United States based on marital status, and to determine if sociodemographic characteristics explain these...
OBJECTIVE
To examine female and male sterilization patterns in the United States based on marital status, and to determine if sociodemographic characteristics explain these patterns.
DESIGN
Survival analysis of cross-sectional data from the female and male samples from the 2006-2010 National Survey of Family Growth.
SETTING
Not applicable.
PATIENT(S)
The survey is designed to be representative of the US civilian noninstitutionalized population, ages 15-44 years.
INTERVENTION(S)
None.
MAIN OUTCOME MEASURE(S)
Vasectomy and tubal sterilization.
RESULT(S)
In the United States, vasectomy is the near-exclusive domain of married men. Never-married and ever-married single men, and never-married cohabiting men, had a low relative risk (RR) of vasectomy (RR = 0.1, 0.3, and 0.0, respectively), compared with men in first marriages. Tubal sterilization was not limited to currently married, or even to ever-married women, although it was less common among never-married single women (RR = 0.2) and more common among women in higher-order marriages (RR = 1.8), compared with women in first marriages. In contrast to vasectomy, differential use of tubal sterilization by marital status was driven in large part by differences in parity.
CONCLUSION(S)
This study shows that being unmarried at the time of sterilization--an important risk factor for poststerilization regret--was much more common among women than men. In addition to contributing to the predominance of female, vs. male, sterilization, this pattern highlights the importance of educating women on the permanency of sterilization, and the opportunity to increase reliance on long-acting reversible contraceptive methods.
Topics: Adolescent; Adult; Contraception Behavior; Cross-Sectional Studies; Female; Health Surveys; Humans; Male; Marital Status; Sex Distribution; Sterilization, Tubal; United States; Vasectomy; Young Adult
PubMed: 25881875
DOI: 10.1016/j.fertnstert.2015.02.036 -
BMJ Open Sep 2022To examine the relationship between baseline union status (ie, including marriage and cohabitation) and mortality, paying attention to gender differentials, through an...
OBJECTIVE
To examine the relationship between baseline union status (ie, including marriage and cohabitation) and mortality, paying attention to gender differentials, through an 11-year follow-up of a large cohort in Thailand.
DESIGN
Cohort data from Thai Cohort Study (TCS) were linked official death records over an 11-year follow-up period.
SETTING
Community-based adults in Thailand.
PARTICIPANTS
87 151 Thai adults participated in TCS cohort.
METHOD
Cox regression models measured longitudinal associations between union status and 11-year mortality.
RESULTS
From 2005 (baseline) to 2016, persons who cohabited and lived with a partner, married persons but not living with a partner and separated/divorced/widowed people were more likely to die compared with those married and living together with a partner. Those who did not have good family support had a higher death risk than those having good family support.Single or cohabiting women had higher risks of mortality than women who were married and living together with a partner throughout follow-up, while separated/divorced/widowed men had higher risks of mortality than counterpart males.
CONCLUSIONS
Our study reveals the protective effect of marriage and living together on mortality in Thailand, an understudied setting where institutionalisation of cohabitation is low leading to a limited mortality protection. Public policies for moderating mortality should thus be gender nuanced, culturally and institutionally specific. Also, we demonstrate that in settings such as Thailand, where marital status is not always defined in the same way as in western cultures, the need to measure cohabitation in locally relevant terms is important.
Topics: Adult; Cohort Studies; Family Characteristics; Female; Humans; Male; Marital Status; Marriage; Thailand
PubMed: 36123057
DOI: 10.1136/bmjopen-2022-062811 -
AMIA ... Annual Symposium Proceedings.... 2019Social Determinants of Health, including marital status, are becoming increasingly identified as key drivers of health care utilization. This paper describes a robust...
Social Determinants of Health, including marital status, are becoming increasingly identified as key drivers of health care utilization. This paper describes a robust method to determine the marital status of patients using structured and unstructured electronic healthcare data from a single academic institution in the United States. We developed and validated a natural language processing pipeline (NLP) for the ascertainment of marital status from clinical notes and compared the performance against two baseline methods: a machine learning n-gram model, and structured data obtained from the electronic health record. Overall our NLP engine had excellent performance on both document-level (F1 0.97) and patient-level (F1 0.95) classification. The NLP Engine had superior performance compared with a baseline machine learning n-gram model. We also observed a good correlation between the marital status obtained from our NLP engine and the baseline structured electronic healthcare data (κ 0.6).
Topics: Electronic Health Records; Female; Hospitals, University; Humans; Machine Learning; Male; Marital Status; Natural Language Processing; Social Determinants of Health; Utah
PubMed: 32308819
DOI: No ID Found -
Scientific Reports Jun 2023This study aimed to investigate the association between marital status and the prognosis of patients with metastatic breast cancer (MBC). Data of patients with MBC were...
This study aimed to investigate the association between marital status and the prognosis of patients with metastatic breast cancer (MBC). Data of patients with MBC were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Patients were classified into married and unmarried groups. Kaplan-Meier analysis with the log-rank test was conducted to compare breast cancer-specific survival (BCSS) and overall survival (OS) between the groups. Univariable and multivariable Cox proportional models were used to determine whether marital status was independently associated with OS, and the Fine-Gray subdistribution hazard method was performed to determine whether marital status was independently associated with BCSS. In total, 16,513 patients with MBC were identified, including 8949 married (54.19%) and 7564 unmarried (45.81%) patients. The married patients were significantly younger [median age (interquartile range), 59.0 (50.0-68.0) vs. 63.0 (53.0-75.0); p < 0.001] and received more aggressive treatments, such as chemotherapy (p < 0.001) and surgery (p < 0.001), than the unmarried patients. Moreover, married patients had higher 5-year BCSS (42.64% vs. 33.17%, p < 0.0001) and OS (32.22% vs. 21.44%, p < 0.0001) rates. Multivariable analysis revealed that marital status was an independent prognostic factor, and married status was associated with a significant reduction in the risk of breast cancer-specific (sub-hazard ratio, 0.845; 95% confidence interval, 0.804-0.888; p < 0.001) and all-cause (hazard ratio, 0.810; 95% confidence interval, 0.777-0.844; p < 0.001) mortality. Unmarried patients had a 15.5% increased risk of breast cancer-specific mortality and a 19.0% increased risk of overall mortality compared with married patients with MBC. BCSS and OS were superior in married populations compared with unmarried populations in most subgroups. Marital status was an independent prognostic indicator for survival in patients with MBC and was associated with significant survival benefits.
Topics: Humans; Female; Breast Neoplasms; Marital Status; Prognosis; Proportional Hazards Models; Kaplan-Meier Estimate; SEER Program
PubMed: 37277464
DOI: 10.1038/s41598-023-36139-8 -
Scientific Reports Nov 2022Social participation is considered one of the central components of successful and healthy aging. This study aimed to examine the moderating role of marital status and...
Social participation is considered one of the central components of successful and healthy aging. This study aimed to examine the moderating role of marital status and living arrangement with social participation and its association with life satisfaction of older Indian adults. Samples of 31,464 individuals aged ≥ 60 years were extracted from the Longitudinal Ageing Study in India, wave-1. Descriptive statistics, bivariate analysis, and multivariable linear regression were performed for the analysis. The moderation effect of marital status and living arrangements on the relationship between social participation and level of life satisfaction among Indian older adults were also analyzed. Overall, life satisfaction among older men was relatively higher than older women in this study. Older adults' involvement in social participation [β = 0.39, p < 0.05], being in marital union [β = 0.68, p < 0.001] and co-residing either with spouse [β = 1.73, p < 0.001] or with other family members [β = 2.18, p < 0.001] were positively related to their greater life satisfaction. Interaction of social participation with marital status showed that participating in social activities can boost life satisfaction only among married older people. Further, moderation effect of social participation with living arrangements showed that older adults who were not involved in social participation but living with a spouse or any other household members had higher life satisfaction, and again participation in social activities increased their life satisfaction to a greater level. The establishment of social clubs and advocating social policies oriented toward meaningful social connections are highly needed, especially for older Indians living alone or currently not in a marital union, which will help to enhance their overall life satisfaction.
Topics: Male; Female; Humans; Aged; Social Participation; Personal Satisfaction; Marital Status; Marriage; Asian People
PubMed: 36446850
DOI: 10.1038/s41598-022-25202-5