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Journal of Clinical and Translational... Jun 2019Biliary mucinous cystadenomas are cystic neoplasms commonly mistaken for simple cysts. They are rare and generally benign tumors, often incidentally found on imaging and... (Review)
Review
Biliary mucinous cystadenomas are cystic neoplasms commonly mistaken for simple cysts. They are rare and generally benign tumors, often incidentally found on imaging and during unrelated surgical interventions. They tend to be slow growing though may reach symptomatic dimensions. Misdiagnosis of biliary mucinous cystadenomas may have serious consequences secondary to their potential for malignant transformation into biliary mucinous cystadenocarcinomas. Here, we review the epidemiology, etiology, pathology, diagnostic modalities, histology, and available treatment methods for mucinous cystadenomas reported in current literature.
PubMed: 31293915
DOI: 10.14218/JCTH.2019.00017 -
International Journal of Surgery Case... Mar 2022Different groups of neoplastic and non-neoplastic conditions can involve the ovaries and the epithelial tumors such as mucinous and Brenner tumors are the most common...
INTRODUCTION
Different groups of neoplastic and non-neoplastic conditions can involve the ovaries and the epithelial tumors such as mucinous and Brenner tumors are the most common neoplastic category.
PRESENTATION OF CASE
This is a case report of a huge mucinous cystadenoma associated with benign Brenner tumor in 56 years old postmenopausal woman, who presented with a fast-growing abdominopelvic mass, and also review the reported articles about this rare occurrence.
DISCUSSION
Mucinous neoplasms of the ovary represent 10%-15% of ovarian neoplasms and about 80% of them are benign. Brenner tumors are a relatively rare epithelial neoplasm of the ovary that usually affect postmenopausal women and most of them are benign. Coexistence of Mucinous cystadenoma with Brenner tumor is a rare mixed epithelial tumor of the ovary.
CONCLUSION
This case report and review of article create awareness among the surgeons and pathologists about rare occurrence of combination of ovarian mucinous cystadenoma and benign Brenner tumor.
PubMed: 35245850
DOI: 10.1016/j.ijscr.2022.106859 -
World Journal of Gastrointestinal... Jun 2020Mucinous cystic neoplasm (MCN) of the pancreas is characterized by mucin-producing columnar epithelium and dense ovarian-type stroma and at risk for malignant...
BACKGROUND
Mucinous cystic neoplasm (MCN) of the pancreas is characterized by mucin-producing columnar epithelium and dense ovarian-type stroma and at risk for malignant transformation. Early diagnosis and treatment of MCN are particularly important.
AIM
To investigate the clinical characteristics of and management strategies for pancreatic mucinous cystadenoma (MCA) and mucinous cystadenocarcinoma (MCC).
METHODS
The clinical and pathological data of 82 patients with pancreatic MCA and MCC who underwent surgical resection at our department between April 2015 and March 2019 were retrospectively analyzed.
RESULTS
Of the 82 patients included in this study, 70 had MCA and 12 had MCC. Tumor size of MCC was larger than that of MCA ( = 0.049). Age and serum levels of tumor markers carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, and CA12-5 were significantly higher in MCC than in MCA patients ( = 0.005, 0.026, and 0.037, respectively). MCA tumor size was positively correlated with serum CA19-9 levels ( = 0.389, = 0.001). Compared with MCC, MCA had a higher minimally invasive surgery rate ( = 0.014). In the MCA group, the rate of major complications was 5.7% and that of clinically relevant pancreatic fistula was 8.6%; the corresponding rates in the MCC group were 16.7% and 16.7%, respectively.
CONCLUSION
Tumor size, age, and serum CEA, CA19-9, and CA12-5 levels may contribute to management of patients with MCN. Surgical resection is the primary treatment modality for MCC and MCA.
PubMed: 32699579
DOI: 10.4251/wjgo.v12.i6.642 -
Canadian Urological Association Journal... 2015Testicular mucinous cystadenomas are rare in urological practice, and their histogenesis, course and management are debated. We report a primary testicular mucinous...
Testicular mucinous cystadenomas are rare in urological practice, and their histogenesis, course and management are debated. We report a primary testicular mucinous cystadenoma in a 54-year old male who presented with left testicular swelling and pain. He denied having a history of cryptorchidism, testicular trauma, infections, urinary complaints, or febrile illnesses. He did not have diabetes, but was on treatment for hypertension. The patient underwent a left inguinal radical orchiectomy, and histological examination of the resected tumour confirmed a primary testicular mucinous cystadenoma. The patient had an uneventful recovery, and is being followed up. Conclusively, urologists need to maintain a high index of suspicion of these tumours and their differentiation from metastatic tumours to ensure optimal therapeutic outcomes.
PubMed: 26600891
DOI: 10.5489/cuaj.3218 -
Diagnostic and Interventional Imaging Jan 2014
Topics: Appendectomy; Appendiceal Neoplasms; Appendix; Cystadenoma, Mucinous; Humans; Image Enhancement; Image Processing, Computer-Assisted; Male; Middle Aged; Mucocele; Tomography, X-Ray Computed
PubMed: 24433760
DOI: 10.1016/j.diii.2013.07.015 -
Journal of Surgical Case Reports Mar 2023Mucinous cystadenoma of the appendix is a rare condition characterized by abnormal mucus accumulation in the appendiceal. Laparoscopic appendectomy is a common approach...
Mucinous cystadenoma of the appendix is a rare condition characterized by abnormal mucus accumulation in the appendiceal. Laparoscopic appendectomy is a common approach worldwide and can be used in the management of mucinous cystadenoma with lower postoperative complication rates. A 30-year-old female had sharp pain localized to the right abdomen for 2 days. It was aggravated by movement and associated with nausea and vomiting. Laboratory findings were normal, but the abdominal computerized tomography scan demonstrated a cystic tumor in the right abdomen dorsal to the cecum and the ascending colon. Diagnostic laparoscopy showed a large cystic mass well-circumscribed encapsulated involving the appendix in the lower right abdomen. After demonstrating pathologic examination, the final diagnosis was mucinous cystadenoma of the appendix. Management of the appendicular mucinous cystadenoma can be successfully achieved through atraumatic laparoscopic excision of the tumor, it is safe, feasible and has a short postoperative recovery period.
PubMed: 36926628
DOI: 10.1093/jscr/rjad097 -
Maedica Sep 2021Bone formation in the ovary is exceedingly rare, except in the setting of dermoid cysts. Here, the author reports a case of incidental finding of heterotopic bone...
Bone formation in the ovary is exceedingly rare, except in the setting of dermoid cysts. Here, the author reports a case of incidental finding of heterotopic bone formation in a mucinous cystadenoma of the ovary in a 45-year-old woman who had underwent a total abdominal hysterectomy and right salpingo-oopherectomy because of hypermenorrhea during last one year with an ultrasonography report of right ovarian cyst and simultaneous multiple uterine leiomyomatas. Microscopic examination of the ovarian cyst revealed a mucinous cystadenoma with the striking finding of several thin plates of lamellar bone identified in fibrous tissue in the cyst wall. Although it is a benign finding and does not seem to have prognostic significance, it may lead to sonographic findings of concern during the evaluation of ovarian cysts.
PubMed: 34925616
DOI: 10.26574/maedica.2020.16.3.538 -
Annals of Medicine and Surgery (2012) May 2023The coexistence of a benign Brenner tumour and a mucinous cystadenoma is rare, and their relationship and origin are still enigmatic and challenging.
UNLABELLED
The coexistence of a benign Brenner tumour and a mucinous cystadenoma is rare, and their relationship and origin are still enigmatic and challenging.
CASE PRESENTATION
In this manuscript, the authors report a case of a 62-year-old nulliparous Syrian woman who presented with severe abdominal distension, which was followed by laparotomy and the excision of a 25×20 cm-cyst; its pathological examination confirmed a benign Brenner's tumour and mucinous cystadenoma.
CLINICAL DISCUSSION
Ovarian Brenner and mucinous are usually benign and can rarely grow asymptomatically to very big sizes. Herein, the authors aim to emphasize the importance of excluding malignancy by pathology examination.
CONCLUSION
Walthard cell nests undergo metaplasia to give rise to different kinds of Brenner and mucinous neoplasm formations according to their genetic alterations. This paper adds to the available literature, which is still poor, by providing evidence of the first case of this rare combination from Syria with a review of different theories of origin and differential diagnoses. More studies directed towards exploring this combination's genetic origin are needed to boost our understanding of ovarian tumours in general.
PubMed: 37228955
DOI: 10.1097/MS9.0000000000000351 -
Surgical Case Reports Mar 2020Pancreatic mucinous cystic neoplasm (MCM) presenting with rupture is extremely rare, and very few studies have followed up patients over the long term after ruptured...
BACKGROUND
Pancreatic mucinous cystic neoplasm (MCM) presenting with rupture is extremely rare, and very few studies have followed up patients over the long term after ruptured mucinous cystadenoma (MCA). We report a case of ruptured MCA of the pancreas with recurrence-free survival for 8 years.
CASE PRESENTATION
A 28-year-old Japanese woman was admitted to the emergency department of a local hospital after experiencing acute abdominal pain. Abdominal computed tomography revealed massive ascites and the presence of a cystic tumor measuring 60 mm in diameter in the pancreatic tail. Conservative therapy with antibiotics and abdominal drainage were performed to treat peritonitis that occurred secondary to the ruptured pancreatic cystic tumor, after which the patient's symptoms improved. The patient was referred to our department for further examination and treatment. We diagnosed a ruptured MCN and performed laparoscopic spleen-preserving distal pancreatectomy. Histopathological findings revealed ovarian-type stroma, which tested positive for estrogen and progesterone receptors by immunohistochemistry. The histopathological diagnosis was MCA. The postoperative course was uneventful, and the patient remains alive without any evidence of recurrence at 8 years postoperatively.
CONCLUSION
A good prognosis is possible even in cases of ruptured MCA. Because of the risk of peritoneal dissemination after ruptured MCA, long-term follow-up is important.
PubMed: 32185526
DOI: 10.1186/s40792-020-00816-x -
Archives of Pathology & Laboratory... May 2001Primary retroperitoneal mucinous cystadenoma is an uncommon tumor found exclusively in women. Herein, we describe a patient who had resection of a large retroperitoneal...
Primary retroperitoneal mucinous cystadenoma is an uncommon tumor found exclusively in women. Herein, we describe a patient who had resection of a large retroperitoneal cystic mass. Histologic, immunohistochemical, and electron microscopic examination of the lining epithelial cells showed features of mesothelial cells in addition to ovarian mucinous cystadenoma. These findings suggest that these tumors arise from inclusions of mesothelial cells and subsequent mucinous metaplasia of the lining cells to form a cystadenoma. Estrogen receptors may be implicated in tumor promotion, explaining the occurrence exclusively in women.
Topics: Adult; Biomarkers, Tumor; Cystadenoma, Mucinous; Female; Humans; Immunohistochemistry; Periodic Acid-Schiff Reaction; Receptors, Estrogen; Retroperitoneal Neoplasms; Tomography, X-Ray Computed
PubMed: 11300948
DOI: 10.5858/2001-125-0691-RMC