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The Journal of Nutrition, Health & Aging Jul 2012Lower muscle strength is associated with a range of adverse health outcomes in later life. The variation in muscle strength between individuals is only partly accounted... (Meta-Analysis)
Meta-Analysis Review
OBJECTIVE
Lower muscle strength is associated with a range of adverse health outcomes in later life. The variation in muscle strength between individuals is only partly accounted for by factors in adult life such as body size and physical activity. The aim of this review was to assess the strength of the association between intrauterine development (indicated by birth weight) and subsequent muscle strength.
DESIGN
Systematic review and meta-analysis of studies that assessed the association between birth weight and subsequent muscle strength.
RESULTS
Nineteen studies met inclusion criteria with 17 studies showing that higher birth weight was associated with greater muscle strength. Grip strength was used as a single measure of muscle strength in 15 studies. Meta-analysis (13 studies, 20 481 participants, mean ages 9.3 to 67.5) showed a 0.86 kg (95% CI 0.58, 1.15) increase in muscle strength per additional kilogram of birth weight, after adjustment for age, gender and height at the time of strength measurement.
CONCLUSION
This review has found consistent evidence of a positive association between birth weight and muscle strength which is maintained across the lifecourse. Future work will be needed to elucidate the biological mechanisms underlying this association, but it suggests the potential benefit of an early intervention to help people maintain muscle strength in later life.
Topics: Birth Weight; Body Height; Body Weight; Databases, Factual; Hand Strength; Humans; Muscle Development; Muscle Strength; Risk Assessment; Risk Factors
PubMed: 22836701
DOI: 10.1007/s12603-012-0053-9 -
Journal of Applied Physiology... Mar 2019Muscle strength, the maximal force-generating capacity of a muscle or group of muscles, is regularly assessed in physiological experiments and clinical trials. An... (Review)
Review
Muscle strength, the maximal force-generating capacity of a muscle or group of muscles, is regularly assessed in physiological experiments and clinical trials. An understanding of the expected variation in strength and the factors that contribute to this variation is important when designing experiments, describing methodologies, interpreting results, and attempting to replicate methods of others and reproduce their findings. In this review (Cores of Reproducibility in Physiology), we report on the intra- and inter-rater reliability of tests of upper and lower limb muscle strength and voluntary activation in humans. Isometric, isokinetic, and isoinertial strength exhibit good intra-rater reliability in most samples (correlation coefficients ≥0.90). However, some tests of isoinertial strength exhibit systematic bias that is not resolved by familiarization. With the exception of grip strength, few attempts have been made to examine inter-rater reliability of tests of muscle strength. The acute factors most likely to affect muscle strength and serve as a source of its variation from trial-to-trial or day-to-day include attentional focus, breathing technique, remote muscle contractions, rest periods, temperature (core, muscle), time of day, visual feedback, body and limb posture, body stabilization, acute caffeine consumption, dehydration, pain, fatigue from preceding exercise, and static stretching >60 s. Voluntary activation, the nervous system's ability to drive a muscle to create its maximal force, exhibits good intra-rater reliability when examined with twitch interpolation (correlation coefficients >0.80). However, inter-rater reliability has not been formally examined. The methodological factors most likely to influence voluntary activation are myograph compliance and sensitivity; stimulation location, intensity, and inadvertent stimulation of antagonists; joint angle (muscle length); and the resting twitch.
Topics: Extremities; Humans; Muscle Strength; Muscle, Skeletal; Reproducibility of Results
PubMed: 30496711
DOI: 10.1152/japplphysiol.00569.2018 -
Scientific Reports Jun 2023Sarcopenia is defined as decreasing in muscle strength and mass, and dynapenia is defined as decreasing in muscle strength and maintained muscle mass. This study...
Sarcopenia is defined as decreasing in muscle strength and mass, and dynapenia is defined as decreasing in muscle strength and maintained muscle mass. This study elucidated the prevalence and characteristics of sarcopenia and dynapenia and evaluate in elderly spinal disorders patients. 1039 spinal disorders patients aged ≥ 65 years were included. We measured age, grip strength, muscle mass, spinal sagittal alignment parameters, low back pain (LBP) scores and health-related quality of life (HR-QoL) scores. Based on the previous reports, patients were categorised into normal group: NG, pre-sarcopenia group: PG, dynapenia group: DG, and sarcopenia group: SG. Pre-sarcopenia, dynapenia, and sarcopenia were found in 101 (9.7%), 249 (19.2%), and 91 (8.8%) patients, respectively. The spinal sagittal alignment parameters, trunk muscle mass, LBP, and HR-QoL scores were significantly worse in DG and SG compared with those in PG and NG. Spinal alignment, trunk muscle mass, and clinical outcomes, including LBP and HR-QoL scores, were maintained in the PG and poor in the DG and SG. Thus, intervention for muscle strength may be a treatment option for changes of spinal sagittal alignment and low back pain.
Topics: Aged; Humans; Sarcopenia; Low Back Pain; Quality of Life; Muscle Strength; Muscle, Skeletal; Hand Strength; Spinal Diseases
PubMed: 37336997
DOI: 10.1038/s41598-023-37125-w -
Jornal Brasileiro de Nefrologia 2023Reduced muscle strength and low-exercise capacity are well documented in adults, but there are few studies examining those impairments in children and adolescents after...
INTRODUCTION
Reduced muscle strength and low-exercise capacity are well documented in adults, but there are few studies examining those impairments in children and adolescents after kidney transplantation. The objective of this study was to evaluate peripheral and respiratory muscle strength and the association with submaximal exercise capacity in children and adolescents after kidney transplant.
METHODS
Forty-seven patients between six and 18 years of age clinically stable after transplantation were included. Peripheral muscle strength (isokinetic and hand-grip dynamometry), respiratory muscle strength (maximal inspiratory and expiratory pressure), and submaximal exercise capacity (six-minute walk test - 6MWT) were assessed.
RESULTS
Patients had a mean age of 13.1 ± 2.7 years and an average of 34 months had elapsed since the transplantation. Flexors of the knee showed a significant reduction in muscle strength (77.3% of predicted) and knee extensors had normal values (105.4% of predicted). Hand-grip strength and maximal respiratory pressures (inspiratory and expiratory) also were significantly lower than expected (p < 0.001). Although distance walked in the 6MWT was significantly lower than predicted (p < 0.001), no significant correlation was found with peripheral and respiratory muscle strength.
CONCLUSION
Children and adolescents after kidney transplantation have reduced peripheral muscle strength of knee flexors, hand-grip, and maximal respiratory pressures. No associations were found between peripheral and respiratory muscle strength and submaximal exercise capacity.
Topics: Adult; Adolescent; Humans; Child; Kidney Transplantation; Muscle Strength; Respiratory Muscles; Hand Strength
PubMed: 37058682
DOI: 10.1590/2175-8239-JBN-2022-0096en -
International Journal of Environmental... Apr 2023Maintaining sufficient muscle strength is fundamental to prevent a decline in basic physical functions such as gait, and is therefore a prerequisite for a healthy...
Maintaining sufficient muscle strength is fundamental to prevent a decline in basic physical functions such as gait, and is therefore a prerequisite for a healthy independent life in older people. However, the relationship between gait parameters and the strength of single muscle groups is reported with inconclusive results. The objective of this study was to analyze the relationship of strength of nine single muscle groups of lower and upper leg muscles as well as handgrip strength for gait parameters in older adults. Sixty-nine independently living older adults participated in the study. Maximum ankle plantar- and dorsiflexion, knee flexion and extension, as well as hip abduction, adduction, flexion, and extension strength, were measured using an isokinetic dynamometer. Additionally, hand grip strength measured via a hand dynamometer was obtained. Walking gait parameters were recorded with a 3D motion capture system on an instrumented treadmill. The relationships between multiple strength and gait variables were analyzed by Pearson's correlation coefficient. Linear regression analyses were performed to identify the predictive ability of muscle strength (normalized to body weight) for gait speed, stride time, stance time, stride length and step width. Multiple significant weak to moderate positive ([r = 0.343, = 0.047]-[r = 0.538, = 0.002]) and negative ([r = -0.340, = 0.046]-[r = 0.593, = 0.001]) correlations that were unequally distributed between both sexes were detected. Significant regression models explained ([r = 16.6%, = 0.015]-[r = 44.3 %, = 0.003]) and ([r = 21.8%, = 0.022]-[r = 36.1%, = 0.044]) of the gait parameter variations for men and women, respectively. The results suggest a sex-specific relevance of single muscle groups for all gait parameters. This may be attributed to anatomical differences and it is important to prevent strength-related changes in gait parameters.
Topics: Male; Humans; Female; Aged; Hand Strength; Gait; Walking; Leg; Muscle Strength
PubMed: 37047976
DOI: 10.3390/ijerph20075362 -
BioMed Research International 2019Muscle strength impairments are related to mobility limitations and other untoward outcomes. This narrative review, therefore, describes considerations relative to the... (Review)
Review
Muscle strength impairments are related to mobility limitations and other untoward outcomes. This narrative review, therefore, describes considerations relative to the definition and measurement of muscle strength. Thereafter, practical options for measuring muscle strength are described and their clinimetric properties are delineated. Information provided herein may help students, clinicians, and researchers select the strength tests best suited to their research needs and limitations.
Topics: Biomedical Research; Humans; Mobility Limitation; Muscle Strength; Muscle, Skeletal
PubMed: 30792998
DOI: 10.1155/2019/8194537 -
PloS One 2024Adolescent childbirth is associated with worse physical function over the long-term. Differential loss of muscle strength during pregnancy and postpartum for adolescents...
Adolescent childbirth is associated with worse physical function over the long-term. Differential loss of muscle strength during pregnancy and postpartum for adolescents compared to adults may be one explanation for this, but research examining these differences is lacking. The objective of this study as to assess hand grip strength and hip adduction muscle strength in adolescents and adults during pregnancy and postpartum. A prospective cohort study was carried out with adolescent (13 to 18 years) and adult (23 to 28 years) primigravid women. Assessments were performed at three timepoints: before the 16th gestational week, during the third trimester, and between the fourth and sixth week postpartum. Hand grip strength (continuous and muscle weakness if ≤ 20.67 kgf) and hip adductor measures (continuous and muscle weakness if ≤ 13.8 kgf) were assessed using dynamometry. Generalized estimating equations modelled longitudinal relationships between muscle weakness and age group. More adolescents had hip adductor weakness than adults in the third trimester of pregnancy (62.5% vs. 31.8%, p < 0.005), which was corroborated by the longitudinal analyses. For all women, there were higher odds of hip adductor weakness in the third trimester (OR = 4.35; p< 0.001) and postpartum (OR = 9.45; p < 0.001) compared to the 16th gestational week. No significant difference in HGS was observed between age groups or across the different timepoints. The higher proportion of hip adductor weakness among adolescents may indicate a need for resistance training during and after pregnancy and physical therapy if weakness or injury is noted.
Topics: Adult; Pregnancy; Humans; Adolescent; Female; Hand Strength; Prospective Studies; Muscle Strength; Postpartum Period; Muscle Weakness
PubMed: 38536784
DOI: 10.1371/journal.pone.0300062 -
International Journal of Environmental... May 2021Functional mobility and muscle strength are well known risk factors for sarcopenia. Furthermore, possible associations have been suggested between predisposing factors...
BACKGROUND
Functional mobility and muscle strength are well known risk factors for sarcopenia. Furthermore, possible associations have been suggested between predisposing factors of sarcopenia and reaction time among the elderly. This study aims to analyze possible associations of functional mobility and muscle strength and reaction times in a population of people aged >60 years.
METHODS
A total of 290 older people (69.35 ± 5.55 years) participated in this study. The following parameters were assessed: optoacoustic lower-limb reaction time (OALLRT); acoustic lower-limb reaction time (ALLRT); optic lower-limb reaction time (OLLRT, using an optical detection system), functional mobility (through the timed up-and-go test) and muscle strength (using a dynamometer).
RESULTS
Our results show that lower values of muscle strength were associated with increased reaction times in OALLRT (β = -0.170; 95% confidence interval -0.011-0.000; R = 0.237; = 0.035) and in ALLRT (β = -0.228; 95% confidence interval -0.011-0.002; R = 0.199; = 0.006).
CONCLUSION
Increased muscle strength (which at low values are risk factors for sarcopenia) was associated with decreased reaction times in people >60 years of age.
Topics: Aged; Cross-Sectional Studies; Hand Strength; Humans; Muscle Strength; Muscle, Skeletal; Physical Functional Performance; Reaction Time
PubMed: 34072660
DOI: 10.3390/ijerph18115893 -
International Journal of Environmental... Feb 2021Handball is among the disciplines that impose a significant degree of asymmetry on the body movement. The aim of the study is to assess the influence of physical effort...
Handball is among the disciplines that impose a significant degree of asymmetry on the body movement. The aim of the study is to assess the influence of physical effort on the occurrence of asymmetry in body musculature and in isometric strength of handball players. The study examined 36 professional handball players. Players' height and body mass were measured as to calculate their body mass indexes (BMIs). Segmental bioelectrical impedance analysis (SBIA) was used to assess: the percentage of fat mass, total muscle mass (MM), musculature of the right and left side of the body, and body segments (trunk, upper and lower limbs). Moreover, grip strength was also measured. The assessment confirmed the existence of discrepancies in the right and left sides of players' bodies for the majority of the parameters. Cross-asymmetry and significant bilateral discrepancies in trunk musculature were also observed. Morphological asymmetry may impact performance in sports since it can cause unfavorable functional changes, which in turn increase the risk of injury and conditions caused by overexertion. Therefore, we believe it is important to emphasize the importance of individualized symmetrization during sports practice and consistent monitoring of the asymmetries occurring in different body parts; this should both improve one's sports results and minimize the risk of injury.
Topics: Hand Strength; Humans; Movement; Muscle Strength; Muscles; Physical Exertion; Sports
PubMed: 33669467
DOI: 10.3390/ijerph18041913 -
Nutrients Aug 2023The main objective of the current study was to perform a systematic literature review with the purpose of exploring the impact of long-chain -3 polyunsaturated fatty... (Meta-Analysis)
Meta-Analysis Review
The main objective of the current study was to perform a systematic literature review with the purpose of exploring the impact of long-chain -3 polyunsaturated fatty acid (LC-3 PUFA) relative to control oil supplementation on muscle strength, with secondary outcomes of muscle mass and physical function in older individuals under conditions of habitual physical activity/exercise. The review protocol was registered with PROSPERO (CRD42021267011) and followed the guidelines outlined in the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement. The search for relevant studies was performed utilizing databases such as PubMed, EMBASE, CINAHL, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL) up to June 2023. Randomized controlled trials (RCTs) in older adults comparing the effects of LC-3 PUFA with a control oil supplement on muscle strength were included. Five studies involving a total of 488 participants (348 females and 140 males) were identified that met the specified inclusion criteria and were included. Upon analyzing the collective data from these studies, it was observed that supplementation with LC-3 PUFA did not have a significant impact on grip strength (standardized mean difference (SMD) 0.61, 95% confidence interval [-0.05, 1.27]; = 0.07) in comparison to the control group. However, there was a considerable level of heterogeneity among the studies ( = 90%; < 0.001). As secondary outcomes were only measured in a few studies, with significant heterogeneity in methods, meta-analyses of muscle mass and functional abilities were not performed. Papers with measures of knee extensor muscle mass as an outcome ( = 3) found increases with LC-3 PUFA supplementation, but studies measuring whole body lean/muscle mass ( = 2) and functional abilities ( = 4) reported mixed results. With a limited number of studies, our data indicate that LC-3 PUFA supplementation has no effect on muscle strength or functional abilities in older adults but may increase muscle mass, although, with only a few studies and considerable heterogeneity, further work is needed to confirm these findings.
Topics: Female; Male; Humans; Aged; Muscle Strength; Hand Strength; Dietary Supplements; Fatty Acids; Muscle, Skeletal; Fatty Acids, Omega-3
PubMed: 37630768
DOI: 10.3390/nu15163579