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Australian Dental Journal Dec 2017The focus on oral manifestations of dengue fever (DF) is not common in the scientific literature and the patient affected can present signs and symptoms that may not be... (Review)
Review
The focus on oral manifestations of dengue fever (DF) is not common in the scientific literature and the patient affected can present signs and symptoms that may not be noticed by dental professionals. This systematic review article was conducted to identify and discuss the oral manifestations related to DF. The electronic databases PubMed, Latin American and Caribbean Literature in Sciences (LILACS), Web of Science and Scopus were searched from November to December 2016 by two authors, simultaneously, using the search terms 'dengue and oral manifestation' combined. We included complete original articles, clinical trials and clinical case reports published in Portuguese, Spanish and English. No limits were applied to the year of publication. Review articles and those with no health outcomes were removed. A limited number of studies aimed to investigate the oral manifestations of DF (N = 25). However, several manifestations were identified in the oral cavity of patients diagnosed with DF such as acute gingival and palate bleeding, dryness of the mouth, taste changes, and erythematous plaque and vesicles on the tongue and palate. Osteonecrosis of jaw associated with DF was also reported. In conclusion, oral manifestations may represent a relevant contributory factor to identify DF disease among patients undergoing dental procedures in general practise.
Topics: Dengue; Dental Plaque; Gingival Hemorrhage; Humans; Mouth Diseases; Palate; Taste Disorders; Xerostomia
PubMed: 28379606
DOI: 10.1111/adj.12516 -
The Chinese Journal of Dental Research 2018To evaluate the use of oral health services, the economic burden of oral diseases and related influential factors in China.
OBJECTIVE
To evaluate the use of oral health services, the economic burden of oral diseases and related influential factors in China.
METHOD
Using the multistage, stratified, equal proportion, random sampling method in the 4th National Oral Health Survey of China conducted in 2015 to 2016, residents aged 3 to 5 years, 12 to 15 years, 35 to 44 years, 55 to 64 years, and 65 to 74 years respectively were recruited, clinically examined and answered a questionnaire. Utilisation of oral health services were assessed in all the age groups and the economic burden of oral diseases in the past 12 months were assessed in the 3 to 5 years and 35 to 74 year-old groups. Chi-squared tests, t tests, correlation analysis and a one-way ANOVA were used to determine the relationships of different factors with utilisation of oral health services and the economic burden of oral diseases.
RESULTS
In the subject groups - 3 to 5 years, 12 to 15 years and 35 to 74 years - the prevalence of the utilisation of oral health services in the past 12 months was 14.6% (5,876/40,353), 23.6% (27,936/118,592), and 20.1% (2,708/13,461), respectively. In all three groups, receiving dental treatment was the most common reason for subjects' recent dental visit. The average dental cost in the past 12 months was 403.43 CNY (median = 100) for 3 to 5-year-old children and 850.83 CNY (median = 300) for adults aged 35 to 74 years old. Area, education and annual household income per person were the socio-economic influential factors. Oral health status, oral hygiene and attitudes to and knowledge of oral health affected the utilisation of oral health services and the economic burden of oral diseases.
CONCLUSION
The percentage of dental service utilisation was relatively low, and the economic burden was high. The related factors for both utilisation of oral health services and the economic burden of oral diseases included living in area, educational attainment, household income, perceived oral health status, and oral hygiene.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; China; DMF Index; Dental Devices, Home Care; Dental Health Services; Educational Status; Female; Gingival Hemorrhage; Health Care Costs; Health Knowledge, Attitudes, Practice; Health Status; Humans; Male; Middle Aged; Oral Health; Oral Hygiene; Rural Population; Toothbrushing; Urban Population
PubMed: 30264044
DOI: 10.3290/j.cjdr.a41086 -
The Neuroradiology Journal Jun 2022Intractable nasal and oropharyngeal hemorrhage may be treated with endovascular embolization, but limited data are available. We sought to evaluate the efficacy, safety,...
BACKGROUND
Intractable nasal and oropharyngeal hemorrhage may be treated with endovascular embolization, but limited data are available. We sought to evaluate the efficacy, safety, and factors associated with rebleeding.
METHODS
A retrospective analysis of consecutive embolizations for nasal and oropharyngeal hemorrhage over a 10-year period at a single institution was performed. Outcomes included procedural success (defined as cessation of hemorrhage in the immediate postoperative period), rebleeding requiring an additional intervention, and procedural complications.
RESULTS
A total of 47 embolizations on 39 patients were included. The mean age was 60 years (standard deviation 16.1), 23.1% of patients were women, and 21 (53.8%) patients had a previously diagnosed head/neck malignancy. Bleeding sites were the nose in 20 patients and oropharynx in 21 (two patients presented with both nasal and oral bleeding). Immediate procedural success was achieved in 45 (95.7%) embolizations. Rebleeding requiring an additional intervention occurred after 11 (23.4%) embolizations at a median of one day after the procedure. In the multivariate analysis, preoperative hypotension (odds ratio 4.78, 95% confidence interval 1.04-24.61) and the use of coils (odds ratio 6.09, 95% confidence interval 1.24-46.69) were associated with rebleeding requiring repeat intervention. Complications included two watershed strokes that were anticipated due to occlusion of the internal carotid artery.
CONCLUSIONS
In our experience endovascular embolization was a safe and effective treatment option for stopping oral and nasal hemorrhage. However, rebleeding was present after 23.4% of treatments and was associated with preoperative hypotension and the use of coils. Further study in a large multi-institutional cohort is warranted.
Topics: Embolization, Therapeutic; Female; Hemorrhage; Humans; Hypotension; Male; Middle Aged; Oropharynx; Retrospective Studies; Treatment Outcome
PubMed: 34477042
DOI: 10.1177/19714009211042893 -
Australian Dental Journal Jun 2016Several new oral anticoagulants have been studied in the past decade, and have now started to enter the market. These drugs are reported to be as effective as, or more... (Review)
Review
Several new oral anticoagulants have been studied in the past decade, and have now started to enter the market. These drugs are reported to be as effective as, or more effective than, warfarin. In Australia, the Therapeutic Goods Administration has approved dabigatran, rivaroxaban and apixaban. The use of these newer anticoagulants is likely to increase in time, and it is important for dentists to have a sound understanding of the mechanisms of action, reversal strategies, and management guidelines for patients taking oral anticoagulants. This article discusses the process of coagulation, available anticoagulants and their monitoring and reversal, and provides clinical advice on the management of patients on anticoagulants who require dental treatment.
Topics: Administration, Oral; Anticoagulants; Australia; Dentistry; Humans; Oral Hemorrhage
PubMed: 26042924
DOI: 10.1111/adj.12344 -
The Chinese Journal of Dental Research Sep 2023To investigate the dental caries status and periodontal status of disabled children and adolescents aged 0 to 18 years in China and provide suggestions for future...
OBJECTIVE
To investigate the dental caries status and periodontal status of disabled children and adolescents aged 0 to 18 years in China and provide suggestions for future policies.
METHODS
The cross-sectional survey included disabled children and adolescents aged 0 to 18 years in welfare institutions across 10 provinces in eastern, central and western regions in China, between November 2013 and May 2015. Oral health examination included dental caries status and periodontal status. The mean score for decayed, missing and filled teeth (dmft/ DMFT) due to caries in primary/permanent dentition, gingival bleeding rate and calculus rate were recorded and statistically evaluated. Data analysis was performed using SPSS 24.0 software (IBM, Armonk, NY, USA), and the level of statistical significance was P < 0.05.
RESULTS
The mean dmft/DMFT values of for groups aged 0 to 5, 6 to 12 and 13 to 18 years were 1.48 ± 3.00, 2.19 ± 2.94 and 1.78 ± 2.93, respectively. The mean scores for the groups aged 0 to 5 (P < 0.05) and 13 to 18 years (P < 0.01) showed a significant difference among different disability types. A significant difference between sexes was found only in the group aged 0 to 5 years (P < 0.05). Gingival bleeding rates were 13.70% for the group aged 0 to 5 years, 24.81% for the group aged 6 to 12 years and 42.06% for the group aged 13 to 18 years, and calculus rates were 5.48%, 22.41% and 47.62% for the three age groups, respectively. The gingival bleeding rate for all three age groups showed a significant difference between different disability types (P < 0.01), whereas calculus rates a showed significant difference only in the groups aged 6 to 12 and 13 to 18 years (P < 0.01).
CONCLUSION
The prevalence of dental caries, gingival bleeding and calculus in disabled children and adolescents in China is high. Disability type was strongly associated with oral health status. Specially designed oral health education and training are necessary for clinical professionals and caregivers.
Topics: Child; Humans; Adolescent; Disabled Children; Cross-Sectional Studies; Dental Caries; Oral Health; China; Gingival Hemorrhage
PubMed: 37732683
DOI: 10.3290/j.cjdr.b4330833 -
Kardiologia Polska Feb 2020Major bleeding (especially intracranial hemorrhage) is the most feared adverse event observed in patients with atrial fibrillation (AF) receiving oral anticoagulation.... (Review)
Review
Major bleeding (especially intracranial hemorrhage) is the most feared adverse event observed in patients with atrial fibrillation (AF) receiving oral anticoagulation. Clinical risk factor-based scores have modest ability to predict major or clinically relevant bleeds, and blood biomarkers are increasingly implemented to improve bleeding prognostication in patients with AF on life‑long anticoagulation. To improve the safety of anticoagulation in the era of non-vitamin K antagonist oral anticoagulants (NOACs, or direct oral anticoagulants [DOACs], including dabigatran, rivaroxaban, apixaban, and edoxaban), specific demographic, clinical, and laboratory variables should be considered. The current review summarizes practical challenges in the management of oral anticoagulation with emphasis on the risk assessment tools, elderly or underweight patients, cancer patients, impact of chronic kidney disease, liver cirrhosis, and thrombocytopenia in the context of bleeding risk in patients with AF.
Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Dabigatran; Hemorrhage; Humans; Pyridones; Rivaroxaban; Stroke
PubMed: 32108755
DOI: 10.33963/KP.15205 -
Neurosurgical Review Apr 2020Oral bacteria DNA has been found in intracranial aneurysms (IA) and a high prevalence of periodontitis was reported in IA patients. We investigated whether periodontitis...
Oral bacteria DNA has been found in intracranial aneurysms (IA) and a high prevalence of periodontitis was reported in IA patients. We investigated whether periodontitis associates with IA formation and aneurysmal subarachnoid hemorrhage (aSAH). First, we compared in a case-control setting the prevalence of periodontal disease in IA patients (42 unruptured IA, 34 ruptured IA) and in age- and gender-matched controls (n = 70) from the same geographical area (Health 2000 Survey, BRIF8901). Next, we investigated whether periodontitis at baseline associated with aSAH in a 13-year follow-up study of 5170 Health 2000 Survey participants. Follow-up data was obtained from national hospital discharge and cause of death registries. Univariate analysis, logistic regression, and Cox-regression were used. Periodontitis (≥ 4mm gingival pocket) and severe periodontitis (≥ 6mm gingival pocket) were found in 92% and 49% of IA patients respectively and associated with IAs (OR 5.3, 95%CI 1.1-25.9, p < 0.000 and OR 6.3, 95%CI 1.3-31.4, p < 0.001, respectively). Gingival bleeding had an even stronger association, especially if detected in 4-6 teeth sextants (OR 34.4, 95%CI 4.2-281.3). Severe periodontitis in ≥ 3 teeth or gingival bleeding in 4-6 teeth sextants at baseline increased the risk of aSAH during follow-up (HR 22.5, 95%CI 3.6-139.5, p = 0.001 and HR 8.3, 95%CI 1.5-46.1, p = 0.015, respectively). Association of periodontitis and gingival bleeding with risk of IA development and aSAH was independent of gender, smoking status, hypertension, or alcohol abuse. Periodontitis and gingival bleeding associate with increased risk for IA formation and eventual aSAH. Further epidemiological and mechanistic studies are indicated.
Topics: Adult; Aged; Aneurysm, Ruptured; Case-Control Studies; Female; Follow-Up Studies; Gingival Hemorrhage; Humans; Intracranial Aneurysm; Logistic Models; Male; Middle Aged; Periodontitis; Prevalence; Registries; Risk Factors; Smoking; Subarachnoid Hemorrhage; Young Adult
PubMed: 30972514
DOI: 10.1007/s10143-019-01097-1 -
BMJ Case Reports Dec 2013A woman in her early 40s presented with a painless ulceration on the right side of the posterior palate, she had an earlier history of similar lesions after the...
A woman in her early 40s presented with a painless ulceration on the right side of the posterior palate, she had an earlier history of similar lesions after the rupturing of blood filled blisters in the oral cavity. On examination, a diffuse erythematous area and ulcers covered with necrotic slough were noticed on the right and left side of the posterior palate and on the right buccal mucosa. On follow-up visit, a large blood filled blister was noticed in the buccal vestibule. We advised routine haematological investigations to rule out any bleeding disorders and direct immunofluorescence of the affected tissue and perilesional areas to rule out autoimmune blistering conditions. Haematological investigations revealed no abnormalities and immunofluorescence testing was negative. A diagnosis of angina bullosa haemorrhagica was made by excluding all other conditions. Symptomatic treatment was given, patient was educated about the condition and reassured.
Topics: Adult; Blister; Diagnosis, Differential; Erythema; Female; Gingival Hemorrhage; Humans; Mouth Mucosa; Mouthwashes; Oral Ulcer; Palate; Treatment Outcome
PubMed: 24334011
DOI: 10.1136/bcr-2013-200352 -
Dental Clinics of North America Jan 2008Oral mucositis is a clinically important and sometimes dose-limiting complication of cancer therapy. Mucositis lesions can be painful, affect nutrition and quality of... (Review)
Review
Oral mucositis is a clinically important and sometimes dose-limiting complication of cancer therapy. Mucositis lesions can be painful, affect nutrition and quality of life, and have a significant economic impact. The pathogenesis of oral mucositis is multifactorial and complex. This review discusses the morbidity, economic impact, pathogenesis and clinical course of mucositis. Current clinical management of oral mucositis is largely focused on palliative measures such as pain management, nutritional support and maintenance of good oral hygiene. However, several promising therapeutic agents are in various stages of clinical development for the management of oral mucositis. These agents are discussed in the context of recently updated evidence-based clinical management guidelines.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Facial Pain; Head and Neck Neoplasms; Humans; Intercellular Signaling Peptides and Proteins; Mouth Mucosa; Oral Hemorrhage; Radiation Injuries; Radiotherapy; Stomatitis; Xerostomia
PubMed: 18154865
DOI: 10.1016/j.cden.2007.10.002 -
Dental and Medical Problems 2018Bacterial plaque control plays a key role in the prevention of caries and periodontal diseases. Hygiene negligence in this respect may influence the state of gingiva,...
BACKGROUND
Bacterial plaque control plays a key role in the prevention of caries and periodontal diseases. Hygiene negligence in this respect may influence the state of gingiva, and - in the long term - the number of lost teeth. The recommended method of mechanical control of dental plaque is tooth brushing twice a day.
OBJECTIVES
The aim of the study was to assess the frequency of tooth brushing, the use of various oral hygiene accessories, the number of preserved teeth, and the occurrence of gingival bleeding in adult Poles, based on a questionnaire study.
MATERIAL AND METHODS
The prepared questionnaire consisted of a general part, assessing the socioeconomic and general medical status of respondents, as well as of specific questions about behavioral actions related to oral hygiene. The study was conducted in 10 Polish cities in Mobile Medical Units as part of the "Health First" campaign in 2017.
RESULTS
The study included 713 respondents: 447 females and 264 males at an average age of 51.1 ±17.6 years. During the previous 6 months, 448 females and 265 males had visited the dentist. The average number of teeth among the respondents aged 35-44 years was 27, and for subjects >65 years old -13. There were statistically significant differences in the frequency of tooth brushing depending on sex and place of residence. The respondents used manual soft and medium toothbrushes more often than electric brushes (p < 0.05). Inhabitants of larger cities, compared to rural residents, used dental floss and toothpicks more frequently (p < 0.05). In total, 271 (50%) of the respondents reported gingival bleeding during tooth brushing. There was a statistically significant association of gingival bleeding with genetic load, and with the use of a manual soft toothbrush and mouthwash.
CONCLUSIONS
Pro-health behaviors of adult Poles in maintaining optimal oral hygiene are unsatisfactory and need improvement.
Topics: Adult; Aged; Dental Devices, Home Care; Dental Health Surveys; Female; Genetic Load; Gingival Hemorrhage; Humans; Jaw, Edentulous, Partially; Male; Middle Aged; Mouthwashes; Oral Hygiene; Poland; Rural Population; Self Report; Toothbrushing; Urban Population; Young Adult
PubMed: 30328310
DOI: 10.17219/dmp/91774