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Journal of Feline Medicine and Surgery Oct 2018Objectives The objective of this study was to identify the renal ultrasonographic (US) findings most strongly associated with azotaemia in cats. Methods US findings in... (Comparative Study)
Comparative Study
Objectives The objective of this study was to identify the renal ultrasonographic (US) findings most strongly associated with azotaemia in cats. Methods US findings in 238 cats with (serum creatinine >180 μmol/l) and 270 cats without azotaemia were compared in a retrospective case-control study. Cats with pre-renal azotaemia or urethral obstruction were excluded. Data extracted from the medical records included age, body weight and body condition score (BCS). Quantitative and subjective US findings were extracted from archived ultrasound images and contemporaneous reports. Results In non-azotaemic cats, mean ± SD renal length was 40.1 ± 5.5 mm. Male cats had larger kidneys than female cats (mean difference 5.2 mm; P = 0.001) and, on average, the right kidney was slightly larger than the left (mean difference 1.6 mm; P = 0.01). Azotaemic cats had significantly lower mean body weight and BCS, and greater mean age and renal pelvic diameter. Renal pelvic diameter was negatively correlated with urine specific gravity (ρ -0.44, P <0.001). Compared with non-azotaemic cats, there was no difference in mean renal length of azotaemic cats because the numbers with enlarged kidneys and small kidneys were similar. Radiologists' subjective assessments of renal size differed markedly between azotaemic and non-azotaemic cats, with azotaemic cats more likely to be recorded falsely as having abnormally small or enlarged kidneys. US findings significantly associated with azotaemia were perinephric fluid (odds ratio [OR] 26.4, 95% confidence interval [CI] 3.4-207.7), small kidneys (OR 8.4, 95% CI 4.0-17.4), hyperechoic renal cortex (OR 4.1, 95% CI 2.2-7.6), loss of corticomedullary differentiation (OR 4.1, 95% CI 1.8-9.6), renal calculi (OR 2.7, 95% CI 1.4-4.9), enlarged kidneys (OR 2.5, 95% CI 1.2-5.5) and dilated renal pelvis (OR 1.6, 95% CI 1.3-1.9). Conclusions and relevance Perinephric fluid was the US finding most strongly associated with azotaemia in this study and may merit more emphasis than it has received to date. Bias in radiologists' subjective assessments of renal size suggests that other subjective findings will also be biased.
Topics: Animals; Azotemia; Case-Control Studies; Cat Diseases; Cats; Creatinine; Female; Kidney Pelvis; Male; Odds Ratio; Retrospective Studies; Ultrasonography
PubMed: 29019448
DOI: 10.1177/1098612X17736657 -
Archivos Espanoles de Urologia Nov 2020Horseshoe kidney is the most common renal fusion anomaly. Its peculiar anatomical characteristics increase the risk of lithiasis formation and always entails a surgical...
OBJECTIVE
Horseshoe kidney is the most common renal fusion anomaly. Its peculiar anatomical characteristics increase the risk of lithiasis formation and always entails a surgical challenge for its treatment.
MATERIAL AND METHODS
We present the cases of men with horseshoe kidneys diagnosed by CT one case of alarge pyelic lithiasis with others of a smaller size in the calyces, and the other of a big solitary lithiasis in renal pelvis. RESULTS: We performed a laparoscopic pyelolitectomy to remove the pyelic lithiasis and we used a flexible cystoscope through a trocar to extract the calyceal stones. The postoperative period was uneventful without evidence of urinary leakage or residual lithiasis. CONCLUSIONS: The laparoscopic approach to lithiasisis a suitable alternative in especially complex cases such as horseshoe kidney. The use of a flexible cystoscope allows to navigate through the renal cavities and extract the lithiasis which cannot be accessed through laparoscopic instruments, improving the efficiency of this approach.
Topics: Fused Kidney; Humans; Kidney; Kidney Calculi; Kidney Calices; Kidney Pelvis; Laparoscopy; Male
PubMed: 33144541
DOI: No ID Found -
BMC Microbiology Nov 2020The long-held notion that, without urinary tract or circulatory infection, bladder urine and blood are sterile biofluids has been disproven. There have been no previous...
BACKGROUND
The long-held notion that, without urinary tract or circulatory infection, bladder urine and blood are sterile biofluids has been disproven. There have been no previous reports on the kidney pelvis urinary microbiome after bladder disinfection in kidney stone patients. This study aimed to determine whether a kidney pelvis urinary microbiome is present after eliminating the influence of the bladder urinary microbiome, whether the microbiome composition is different in patients with stone kidney pelvis (SKP) and non-stone kidney pelvis (NSKP), and the correlation between SKP and patient clinical characteristics.
RESULTS
Comparisons of bacterial diversity and community structure exhibited that urine in bladder was similar to SKP and NSKP. However, the comparisons showed that urine samples were different from blood. The most common operational taxonomic units were shared by all three types of urine samples. Corynebacterium was significantly higher in SKP compared to NSKP. Several bacteria were associated with patient characteristics, including Lactobacillus, which was positively correlated with fasting blood glucose, and Prevotella was negatively correlated with BMI. Lactobacillus was significantly higher in SKP compared to blood but not in NSKP compared to blood.
CONCLUSIONS
The composition of the kidney pelvis urinary microbiome after disinfection of the bladder and its similarity to the bladder microbiome indicate that bladder urine can be used to replace kidney pelvis urine in microbiome research. Additionally, the comparison of SKP and NSKP and clinical associations suggest that the occurrence of kidney stones is responsible for the SKP urinary microbiome.
Topics: Adult; Aged; Bacteria; Blood; Female; Humans; Kidney; Kidney Calculi; Male; Microbiota; Middle Aged; Pelvis; RNA, Ribosomal, 16S; Urinary Bladder; Urinary Tract
PubMed: 33153435
DOI: 10.1186/s12866-020-01992-4 -
BMJ Case Reports May 2021We describe the first reported case of transient distal ureteric obstruction attributed to post-surgical oedema in a patient with a solitary kidney. This occurred...
We describe the first reported case of transient distal ureteric obstruction attributed to post-surgical oedema in a patient with a solitary kidney. This occurred following combined pelvic floor repair and sacrospinous fixation for recurrent pelvic organ prolapse and manifested clinically as anuria, radiological hydroureter and acute kidney injury in the postoperative period. The transient nature of this obstruction, which was managed by a temporary percutaneous nephrostomy, indicates that it was caused by ureteric compression secondary to soft tissue oedema following surgery. We highlight the importance of this potential complication in females with a history of nephrectomy, unilateral renal tract anomalies or severely diminished renal reserve.
Topics: Anuria; Female; Humans; Nephrostomy, Percutaneous; Pelvic Floor; Pelvic Organ Prolapse; Ureteral Obstruction
PubMed: 33986003
DOI: 10.1136/bcr-2020-238669 -
Neurourology and Urodynamics Jun 2023To describe the methods for the in-person assessment of the RISE FOR HEALTH (RISE) study, a population-based multicenter prospective cohort study designed to identify...
OBJECTIVES
To describe the methods for the in-person assessment of the RISE FOR HEALTH (RISE) study, a population-based multicenter prospective cohort study designed to identify factors that promote bladder health and/or prevent lower urinary tract symptoms in adult women, conducted by the Prevention of Lower Urinary Tract Symptoms Research Consortium (PLUS).
METHODS AND RESULTS
A subset of RISE participants who express interest in the in-person assessment will be screened to ensure eligibility (planned n = 525). Eligible consenting participants are asked to complete 15 physical assessments in addition to height and weight, to assess pelvic floor muscle function, musculoskeletal (MSK) status, and pain, and to provide urogenital microbiome samples. Pelvic floor muscle assessments include presence of prolapse, strength, levator attachment integrity (tear) and myofascial pain. MSK tests evaluate core stability, lumbar spine, pelvic girdle and hip pain and function. Participants are asked to complete the Short Physical Performance Battery to measure balance, lower extremity strength, and functional capacity. All participants are asked to provide a voided urine sample and a vaginal swab for microbiome analyses; a subset of 100 are asked to contribute additional samples for feasibility and validation of a home collection of urinary, vaginal, and fecal biospecimens.
RESULTS
Online and in-person training sessions were used to certify research staff at each clinical center before the start of RISE in-person assessments. Standardized protocols and data collection methods are employed uniformly across sites.
CONCLUSIONS
The RISE in-person assessment is an integral portion of the overall population-based RISE study and represents an innovative approach to assessing factors hypothesized to promote bladder health and/or prevent lower urinary tract symptoms. Data collected from this assessment will be used to prioritize future research questions and prevention strategies and interventions. This description of the assessment methods is intended to provide methodologic transparency and inform other researchers who join efforts to understand and improve bladder health.
Topics: Adult; Humans; Female; Prospective Studies; Pelvic Floor; Urinary Bladder; Lower Urinary Tract Symptoms; Pain
PubMed: 36573845
DOI: 10.1002/nau.25108 -
Journal of Feline Medicine and Surgery Oct 2023A retrospective multicenter case series of renal fusion anomalies in cats was investigated. The aim of this study was to describe the imaging characteristics...
CASE SERIES SUMMARY
A retrospective multicenter case series of renal fusion anomalies in cats was investigated. The aim of this study was to describe the imaging characteristics (radiography, ultrasonography and CT) of renal ectopia and fusion in cats. A total of 13 feline patients (median age 9 years) were included in this multicentric retrospective study. Ultrasound was available in 12/13 cases, radiographs in 4/13 cases and CT in 3/13 cases. Of the 13 cases, seven were left to right fusions, four were right to left fusions, one was on the midline and one was in the pelvic inlet. Adopting a human classification system, there were five lump kidneys, four disc kidneys, one horseshoe kidney, one caudal ectopia, one L-shaped kidney and one pelvic kidney. In 2/13 cases, additional congenital malformations were noted, including an azygous continuation of the caudal vena cava and a peritoneal-pericardial diaphragmatic hernia.
RELEVANCE AND NOVEL INFORMATION
This study provides further description of the imaging findings in feline patients with fused renal ectopia. The morphologic characteristics of the fused kidneys in cats appear similar to what is published in the human literature. Renal fusion might be an incidental finding in cats, but further investigations are necessary to determine their clinical relevance.
Topics: Humans; Cats; Animals; Fused Kidney; Retrospective Studies; Kidney Diseases; Kidney; Radiography; Cat Diseases
PubMed: 37791875
DOI: 10.1177/1098612X231196810 -
International Braz J Urol : Official... 2024To evaluate the surgical anatomy of the kidney collecting system through a narrative review of the literature, highlighting its importance during diagnosis and its... (Review)
Review
OBJECTIVE
To evaluate the surgical anatomy of the kidney collecting system through a narrative review of the literature, highlighting its importance during diagnosis and its approach during surgical procedures for the treatment of renal stones.
MATERIAL AND METHODS
We carried out a review about the anatomy of the kidney collecting system. We analyzed papers published in the past 40 years in the databases Pubmed, Embase and Scielo, and we included only papers in English and excluded case reports, editorials and opinions of specialists.
RESULTS
Renal collecting system could be divided in four groups: A1 - kidney midzone (KM), drained by minor calyx that are dependent on the superior or the inferior caliceal groups; A2 - KM drained by crossed calyx, one draining into the superior caliceal group and another draining into the inferior caliceal group; B1 - KM drained by a major caliceal group independent of both the superior and inferior groups; and B2 - KM drained by minor calyx entering directly into the renal pelvis. Some details and anatomic variations of the collecting system are related to clinical and radiological aspects, particularly perpendicular calyces, interpyelocalyx space, position of calyces in relation to renal border, classification of the renal collecting system, infundibular diameter and the angle between the lower infundibulum and renal pelvis.
CONCLUSION
The knowledge of intra-renal collecting system divisions and variations as the angle between the renal pelvis and lower infundibula, position of the calices in relationship with renal edge and the diameter and position of the calyces are important for the planning of minimally invasive renal surgeries.
Topics: Humans; Kidney; Kidney Calices; Kidney Pelvis; Kidney Calculi; Databases, Factual
PubMed: 38386787
DOI: 10.1590/S1677-5538.IBJU.2024.9901 -
Internal Medicine (Tokyo, Japan) Jun 2022
Topics: Humans; Kidney; Kidney Diseases
PubMed: 34776491
DOI: 10.2169/internalmedicine.8423-21 -
Acta Medica Indonesiana Jul 2022Obstructive uropathy can have many causes and can manifest as supravesical, vesical, or infravesical levels of obstruction. Treatment of obstructive uropathy, whether...
Obstructive uropathy can have many causes and can manifest as supravesical, vesical, or infravesical levels of obstruction. Treatment of obstructive uropathy, whether definitive or temporary, has a risk of complications or could worsen the patient's quality of life. Thus, knowledge of the parameters that predict recoverability of renal function after obstructive uropathy treatment is essential for patients and their families. Several studies have evaluated many factors that might potentially predict recoverability of renal function after obstruction release and these essentially are divided into factors predicting unilateral or bilateral obstruction. Almost all unilateral obstruction studies used ureteropelvic junction obstruction cases as their subjects and utilized nuclear scan renography to evaluate kidney recoverability. Factors confirmed as predicting factors for recoverability of renal function were age, hemoglobin level, BUN-to-creatinine ratio, postoperative urine volume and sodium excretion, cortical thickness, type of renal pelvis, hydronephrosis grade, corticomedullary differentiation, parenchymal echogenicity, renal resistive index, and initial kidney function. Thus, these studies all had different criteria for defining the recovery of renal function, and this might explain the differences observed from study to study.
Topics: Adult; Creatinine; Hemoglobins; Humans; Kidney; Quality of Life; Sodium
PubMed: 36156471
DOI: No ID Found -
The Kaohsiung Journal of Medical... Apr 2017In spite of the fact that urologic surgical techniques used by urologists are becoming more and more minimally invasive and easier because of developing technologies,...
In spite of the fact that urologic surgical techniques used by urologists are becoming more and more minimally invasive and easier because of developing technologies, surgical approaches for the urinary stones in kidneys with abnormal anatomy are still confusing. The objective of this article is to determine the treatment options in these kidneys. For this purpose, between 2005 and 2015, we retrospectively evaluated patients operated for urolithiasis with various congenital renal anomalies in five referral urology clinics in our country. Of the 178 patients (110 male, 60 female), 96 had horseshoe kidneys, 42 had pelvic ectopic kidneys (PEKs), and 40 had isolated rotation anomalies (IRAs) of the kidney. We evaluated the patients for stone-free rate (SFR), mean operation time, mean hospitalization time, and complication rate. In horseshoe kidney, SFRs for retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) groups were 72.2% and 90%, respectively. In PEKs, these rates were 83.6% and 100% for RIRS and laparoscopic pyelolithotomy, respectively. SFRs in kidneys with IRA were 75% for RIRS and 83.3% for PNL. The mean operation time for RIRS and PNL groups in horseshoe kidney was 40.5±11.2 minutes and 74.5±19.3 minutes, respectively. In PEKs, these times were 52.1±19.3 minutes and 53.1±24.3 minutes for RIRS and laparoscopic pyelolithotomy, respectively. Mean operation time in kidneys with IRA was 48.7±14.4 minutes for RIRS and 53.2±11.3 minutes for PNL. Mean hospitalization times for RIRS and PNL groups in horseshoe kidneys were 1.4±0.7 days and 2.2±1.4 days, respectively. In PEKs, these times were 2.7±1.8 days and 1.9±0.4 days for RIRS and laparoscopic pyelolithotomy, respectively. Mean operation time in kidneys with IRA was 1.5±0.9 days for RIRS and 1.8±0.6 days for PNL. The results of our study showed that RIRS could be used in all of types of abnormal kidneys with small- and medium-sized renal calculi safely and satisfactorily.
Topics: Adult; Demography; Female; Fluoroscopy; Humans; Kidney; Kidney Calculi; Length of Stay; Male; Middle Aged
PubMed: 28359409
DOI: 10.1016/j.kjms.2017.01.003