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Acta Otorrinolaringologica Espanola 2013
Topics: Hernia; Herniorrhaphy; Humans; Male; Middle Aged; Pharyngeal Diseases
PubMed: 22498371
DOI: 10.1016/j.otorri.2012.02.003 -
Journal of Veterinary Internal Medicine Jul 2019Characterization of the clinical signs, response to treatment and prognosis can be useful information for decision-making when evaluating cattle with pharyngeal trauma.
BACKGROUND
Characterization of the clinical signs, response to treatment and prognosis can be useful information for decision-making when evaluating cattle with pharyngeal trauma.
OBJECTIVE
To describe the signalment, history, clinicopathologic, endoscopic, ultrasonographic, radiographic, and postmortem findings as well as treatments and outcomes of cattle diagnosed with pharyngeal perforation/trauma.
ANIMALS
Review of medical records of cattle >1 month of age admitted to a Veterinary Teaching Hospital from 1995 to 2017.
METHODS
Retrospective study. Review of medical records of cattle with pharyngeal perforation/trauma identified by oral or endoscopic examination in hospital setting.
RESULTS
Twenty-seven out of 7550 (0.36%) cases met the inclusion criteria. Pharyngeal perforation/trauma was associated with the administration of a bolus in 24 (89%) cows and a magnet in 3 (11%) cases. The boluses contained monensin (n = 12), calcium salts (n = 5), iodine (n = 1), aspirin (n = 1), vitamins (n = 1), and an unknown product (n = 4). The primary clinical signs were dysphagia, swelling of the throatlatch, subcutaneous emphysema, swelling, and pain on palpation of the throatlatch. Seventeen (63%) cows were discharged whereas 10 (37%) were euthanized. Median time between the suspected traumatic event and hospital admission was 1 day (range: 0.5-3 days) and 2 days (range: 0.5-15) for surviving and nonsurviving cattle, respectively. All 5 cows that suffered pharyngeal trauma associated with administration of calcium salt bolus were euthanized.
CONCLUSIONS AND CLINICAL IMPORTANCE
Pharyngeal trauma is a rare condition in cattle. Case fatality rate increases if not diagnosed and treated promptly. The nature of the penetrating foreign body influences the outcome.
Topics: Administration, Oral; Animals; Calcium Compounds; Cattle; Female; Foreign Bodies; Magnets; Monensin; Pharyngeal Diseases; Pharynx; Prognosis; Retrospective Studies
PubMed: 31058361
DOI: 10.1111/jvim.15510 -
Annals of Palliative Medicine Sep 2023Pharyngocutaneous fistula is a serious complication after head and neck reconstruction and concurrent chemoradiotherapy, yet no consensus or practical protocols... (Review)
Review
Pharyngocutaneous fistula is a serious complication after head and neck reconstruction and concurrent chemoradiotherapy, yet no consensus or practical protocols regarding the surgical timing and specific procedures could be found in the current literature. The authors aimed to review their clinical experience in surgical management and develop an algorithmic approach accordingly. A retrospective review of all hypopharyngeal cancer patients who developed pharyngocutaneous fistula during 2017 to 2021 at E-Da Hospital was conducted. Seventeen patients developed pharyngocutaneous fistula in all 321 pharyngeal cancer admissions during this period. Three patients received interventions at acute stage (≤2 weeks), with two direct repairs Three patients received interventions at acute stage (≤2 weeks), with two direct repairs and one regional flap coverage then negative pressure wound therapy. Nine received interventions at subacute stages (2 weeks to 3 months), with 4 resolved after debridement and direct repair yet another 4 underwent regional flap reconstruction and 1 free flap reconstruction. Five chronic fistula (>3 months) received secondary reconstructions utilizing a double-layered repair of local turn-over flaps for the internal mucosal opening and another flap harvest (four regional flaps and one free flap) to cover the outer skin defect. All patients after the palliative surgery achieved complete remission of fistula at follow follow-up. Different conservative and surgical approaches should be adopted according to the acute, subacute, and chronic stages of pharyngocutaneous fistula after palliative head and neck reconstructions.
Topics: Humans; Cutaneous Fistula; Head and Neck Neoplasms; Pharyngeal Diseases; Plastic Surgery Procedures; Postoperative Complications; Retrospective Studies; Surgical Flaps
PubMed: 37691332
DOI: 10.21037/apm-22-1475 -
British Medical Journal Dec 1979
Topics: Diverticulum; Humans; Pharyngeal Diseases
PubMed: 119566
DOI: No ID Found -
Revista Espanola de Enfermedades... Feb 2004
Review
Topics: Algorithms; Deglutition Disorders; Humans; Mouth Diseases; Pharyngeal Diseases
PubMed: 15255021
DOI: 10.4321/s1130-01082004000200005 -
Journal of the Chinese Medical... Jun 2014We describe a rare case of entomophthoromycosis of the pharynx in a previously healthy patient, unlike other fungal infections which are seen as opportunistic infections...
We describe a rare case of entomophthoromycosis of the pharynx in a previously healthy patient, unlike other fungal infections which are seen as opportunistic infections in immunocompromised hosts. This infection is commonly seen in subtropical and tropical areas of Africa, America, and Asia. Painless, erythematous, indurated plaques of subcutaneous tissue are characteristic of this infection. There are currently no standard antifungal regimens for this infection, making treatment difficult. An endoscopic surgical wide resection of the lesion was performed, itraconazole was administered, and the patient improved clinically.
Topics: Adult; Antifungal Agents; Entomophthorales; Humans; Itraconazole; Male; Pharyngeal Diseases; Zygomycosis
PubMed: 24746408
DOI: 10.1016/j.jcma.2014.02.013 -
International Archives of Allergy and... 2022Mast cells (MCs) are involved in several biological processes, such as defense against pathogens, immunomodulation, tissue repair after injury, and angiogenesis. MCs... (Review)
Review
Mast cells (MCs) are involved in several biological processes, such as defense against pathogens, immunomodulation, tissue repair after injury, and angiogenesis. MCs have been shown to change from protective immune cells to potent pro-inflammatory cells, influencing the progression of many pathological conditions, including autoimmune diseases and cancers. The role of MCs in the pathogenesis of rhinopathies has often been underestimated, since previous studies have focused their attention on eosinophils and neutrophils, while MCs were considered involved exclusively in allergic rhinitis. However, recent nasal cytology findings have shown the involvement of MCs in several rhinopathies, such as NARMA, NARESMA, and CRSwNP. These recent evidences highlight the crucial role that MCs play in orchestrating the inflammation of the nasal mucosa, through complex biological mechanisms, not yet fully understood. In this context, a better understanding of these mechanisms is fundamental for practicing Precision Medicine, which requires careful population selection and stratification into subgroups based on the phenotype/endotype of the patients, in order to guarantee the patient a tailored therapy. Based on this background, further studies are needed to understand the pathophysiological mechanisms involving MCs and, consequently, to develop targeted therapies aimed to obtain a selective inhibition of tissue remodeling and preventing MC-mediated immune suppression.
Topics: Animals; Biomarkers; Cell Plasticity; Disease Management; Disease Susceptibility; Humans; Inflammation; Mast Cells; Neovascularization, Physiologic; Pharyngeal Diseases; Phenotype; Respiratory Physiological Phenomena; Respiratory System; Rhinitis
PubMed: 34551414
DOI: 10.1159/000518924 -
Medicine Feb 2019It was aimed to report 5 cases of pharyngeal hairy polyps, and to summarize the characteristics combined with literature review.Five cases with pathological diagnosis of... (Observational Study)
Observational Study
It was aimed to report 5 cases of pharyngeal hairy polyps, and to summarize the characteristics combined with literature review.Five cases with pathological diagnosis of pharyngeal hair polyps were diagnosed and treated in our department from June, 2006 to October, 2016, and retrospective analysis of their clinical data was performed. Among the 5 cases, there were 1 male and 4 female, with the age of 2 days to 26 months old. After birth, these patients were accompanied by stridor, difficulty breathing, snoring, feeding difficulties, and slow weight gain.Gray mass in the stem original from the pharynx was found in all 5 cases, with the surface hair-covering. The polyp resections were performed under general anesthesia, with the complete removal of polyp along the pars basilaris during surgery smoothly. The operation during was 5 to 20 minute, with an average of 12 minute, and there was little hemorrhage during operation. Symptoms disappeared completely after the surgery, and follow-up was performed for 1 year without recurrence shown.Pharyngeal hairy polyp is a rare non-malignant clinical disease, mainly caused by symptoms in respiratory tract obstruction. Complete removal of polyps along the pars basilaris is an effective treatment, with no recurrence case reported after surgery.
Topics: Child, Preschool; Female; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Pharyngeal Diseases; Polyps; Retrospective Studies
PubMed: 30702604
DOI: 10.1097/MD.0000000000014305 -
Sexually Transmitted Diseases Apr 2023Current guidance from the US Centers for Disease Control and Prevention recommends empiric treatment for persons exposed to sexually transmitted infections, including...
BACKGROUND
Current guidance from the US Centers for Disease Control and Prevention recommends empiric treatment for persons exposed to sexually transmitted infections, including Neisseria gonorrhoeae ( NG ). As an antimicrobial stewardship measure, some clinics now recommend a test and treat strategy, but reliance on urogenital testing only may miss cases.
METHODS
We conducted a descriptive analysis of pharyngeal NG infection in men who have sex with women (MSW) and women seeking care at a sexual health clinic in Seattle, WA, from February 2017 to July 2021 because of sexual contact to a partner diagnosed with gonorrhea. We also explored behavioral factors associated with pharyngeal NG positivity (by culture or nucleic acid amplification test by χ2 analysis.
RESULTS
Among 352 NG contacts tested for urogenital or pharyngeal infection, 34% were positive for NG at ≥1 anatomic site (27% for MSW and 40% for women). Among 161 NG contacts tested at the pharynx, 30% (n = 48) were positive: 20% of 54 MSW (n = 11) and 35% (n = 37) of 107 women. If only urogenital testing were performed, 36% of MSW NG infections (n = 5) and 19% of female NG infections (n = 9) would have remained unidentified.
CONCLUSIONS
Pharyngeal NG is relatively common among MSW and women who have been exposed to NG, and likely represents an underdiagnosed reservoir of NG infection. If empiric treatment is abandoned in favor of testing and treating, testing the throats of heterosexuals will be necessary.
Topics: Male; Female; Humans; Gonorrhea; Sexual Partners; Heterosexuality; Sexual Behavior; Neisseria gonorrhoeae; Pharynx; Homosexuality, Male; Chlamydia Infections; Pharyngeal Diseases
PubMed: 36548117
DOI: 10.1097/OLQ.0000000000001760 -
Ear, Nose, & Throat Journal Jan 2023
Topics: Humans; Pharyngeal Diseases; Cutaneous Fistula
PubMed: 33355000
DOI: 10.1177/0145561320984993