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Edinburgh Medical Journal Oct 1872
PubMed: 29639268
DOI: No ID Found -
Indian Journal of Sexually Transmitted... 2022Syringomas commonly occur in women over the face, neck, and chest. They are usually asymptomatic and mainly of cosmetic concern. The vulva is an uncommon site for...
Syringomas commonly occur in women over the face, neck, and chest. They are usually asymptomatic and mainly of cosmetic concern. The vulva is an uncommon site for syringomas. A 45-year-old woman had asymptomatic lesions over the face, of 28 years duration and presented with vulvar papules, associated with severe pruritus for the past 2 months. Clinical and histopathological examination confirmed them to be syringomas. Coexistent facial and vulvar syringomas are rare. Further, vulvar syringomas presenting as pruritus vulvae is still rarer. We report a case with severe pruritus vulvae causing sufficient distress to seek medical care, which is remarkably unusual.
PubMed: 35846546
DOI: 10.4103/ijstd.IJSTD_1_20 -
Journal of Ethnopharmacology Feb 2024The genus Alchemilla L. (lady's mantle) comprises 1000 species, of which more than 300 have been characterized from Europe. Notably, as folk medicines, Alchemilla... (Review)
Review
ETHNOPHARMACOLOGICAL RELEVANCE
The genus Alchemilla L. (lady's mantle) comprises 1000 species, of which more than 300 have been characterized from Europe. Notably, as folk medicines, Alchemilla species have long been prescribed for the treatment of dysmenorrhea, pruritus vulvae, menopausal complaints, and related diseases in women. This review summarizes the traditional uses, highlights promising plant species, and focuses on phytochemical and biological studies to highlight future areas of research.
AIM OF THE REVIEW
This literature review aims to provide a comprehensive overview of Alchemilla species, covering their botany, traditional uses, phytochemistry, and biological and pharmacological activities, and to summarize the current research status to better understand the application value of Alchemilla plants in modern phytotherapy.
MATERIALS AND METHODS
The search strategy utilized the major thematic platforms Reaxys, Web of Science, Google Scholar, Scopus, ScienceDirect, PubMed, the USDA Plant Database and Kew Science (Royal Botanic Gardens) and was performed with the term Alchemilla. These platforms were systematically searched for articles published from 1960 to 2023.
RESULTS AND DISCUSSION
Alchemilla species, as members of the Rosaceae family, produce tannins, phenolic acids, flavonoids, anthocyanins, coumarins, triterpenes and violet compounds. Effort has been made with this comprehensive review of Alchemilla plants to highlight the recent developments and milestones achieved in modern phytochemistry and phytotherapy, underlaying a broad spectrum of the activities of these plants, such as antioxidant, anti-inflammatory, neuroprotective, antimicrobial, antiobesity, cardiovascular, anticancer, and wound healing effects.
CONCLUSIONS
An increasing number of studies on the plants in the Alchemilla genus have provided data about the main constituents and their importance in modern medicine. Both in vitro and in vivo studies have indicated that Alchemilla plants possess an extensive spectrum of biological activities. Regardless of the remarkable medical potential of Alchemilla extracts, clinical studies are limited and need to be performed to produce safer and less expensive plant-based drugs.
Topics: Female; Humans; Ethnopharmacology; Plants, Medicinal; Alchemilla; Rosaceae; Anthocyanins; Phytotherapy; Plant Extracts; Phytochemicals
PubMed: 37981119
DOI: 10.1016/j.jep.2023.117439 -
British Medical Journal Jan 1969
Topics: Candidiasis, Vulvovaginal; Clothing; Contraceptives, Oral; Female; Humans; Pruritus Vulvae
PubMed: 5761816
DOI: 10.1136/bmj.1.5636.120-e -
CMAJ : Canadian Medical Association... Jun 2014
Review
Topics: Biopsy; Chronic Disease; Cognitive Behavioral Therapy; Diagnosis, Differential; Female; Humans; Middle Aged; Photochemotherapy; Postmenopause; Pruritus Vulvae
PubMed: 24549132
DOI: 10.1503/cmaj.130665 -
British Medical Journal Apr 1973
Topics: Anti-Infective Agents; Clothing; Contraceptives, Oral; Deodorants; Detergents; Drug Hypersensitivity; Female; Humans; Pruritus Vulvae
PubMed: 4700020
DOI: 10.1136/bmj.2.5860.243 -
Anaesthesia Mar 2004
Topics: Adult; Antiemetics; Dexamethasone; Female; Humans; Postoperative Nausea and Vomiting; Pruritus Vulvae
PubMed: 14984543
DOI: 10.1111/j.1365-2044.2004.03696.x -
Journal of Lower Genital Tract Disease Jul 2015Chronic vulvar pruritus and vulvodynia are common vulvar diseases. The aim of this study was to compare gynecologic and sexual and physical abuse histories from patients...
OBJECTIVE
Chronic vulvar pruritus and vulvodynia are common vulvar diseases. The aim of this study was to compare gynecologic and sexual and physical abuse histories from patients with these diagnoses and from healthy controls.
MATERIALS AND METHODS
Questionnaires were self-completed by patients diagnosed with vulvar itch-scratch (n = 93), patients diagnosed with vulvodynia (n = 232), and patients presenting for annual gynecologic examinations (n = 104) at the University of Michigan Hospitals, Ann Arbor, MI.
RESULTS
Patients who came for annual examinations were less likely to report past gynecologic infections (p < .05) and indicated higher interest in and more frequent sexual activity than the other 2 groups (p = .003). Vulvodynia patients had the highest scores on the McGill Pain Questionnaire (p < .001). Subjects with either vulvar disorder were more likely to self-report a history of gynecologic infections than annual examination controls. Rates of sexual (p = .78) and physical abuse (p = .12) were similar for all 3 groups.
CONCLUSIONS
Patients with vulvar pruritus and vulvodynia report similar rates of sexual and physical abuse.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Hospitals, Teaching; Humans; Interpersonal Relations; Michigan; Middle Aged; Pain Measurement; Parity; Physical Abuse; Pruritus Vulvae; Risk Factors; Sex Offenses; Sexual Behavior; Sexually Transmitted Diseases; Surveys and Questionnaires; Vulvodynia; Women's Health; Young Adult
PubMed: 26111040
DOI: 10.1097/LGT.0000000000000075 -
British Medical Journal Mar 1881
PubMed: 20749802
DOI: 10.1136/bmj.1.1053.327 -
Medical Examiner (Philadelphia, Pa.) Nov 1848
PubMed: 38120827
DOI: No ID Found