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Journal of Medical Radiation Sciences Jun 2023
Topics: Humans; Nuclear Medicine; Radiation Protection; Caregivers; Radiography; Radionuclide Imaging; Radiation Dosage
PubMed: 37092304
DOI: 10.1002/jmrs.683 -
Cardiovascular and Interventional... Jun 2021Patients in fluoroscopically guided interventions (FGI) may be exposed to substantial radiation dose levels (SRDL). The most commonly reported adverse reactions are skin... (Review)
Review
Patients in fluoroscopically guided interventions (FGI) may be exposed to substantial radiation dose levels (SRDL). The most commonly reported adverse reactions are skin injuries with erythema or necrosis. It is therefore important for the interventional radiologist to know deterministic effects with their threshold doses. If possible all relevant modality parameters should be displayed on the interventionalists screen. Dosimetric parameters should be displayed in digital imaging and communications in medicine (DICOM) units and stored as DICOM Radiation Dose Structured Report (RDSR). The peak skin dose (PSD) is the most relevant risk parameter for skin injuries. Dose management systems (DMS) help optimising radiation exposure of patients. However, their calculation of skin dose maps is only available after a FGI. Therefore, dose maps and PSD should preferably be calculated and displayed in real time by the modality.
Topics: Fluoroscopy; Humans; Radiation Dosage; Radiography, Interventional; Radiometry
PubMed: 33660065
DOI: 10.1007/s00270-021-02772-x -
Hong Kong Medical Journal = Xianggang... Apr 2013Dicentric assay is the international gold standard for cytogenetic biodosimetry after radiation exposure, despite being very labour-intensive, time-consuming, and highly... (Review)
Review
Dicentric assay is the international gold standard for cytogenetic biodosimetry after radiation exposure, despite being very labour-intensive, time-consuming, and highly expertise-dependent. It involves the identification of centromeres and structure of solid-stained chromosomes and the enumeration of dicentric chromosomes in a large number of first-division metaphases of cultured T lymphocytes. The dicentric yield is used to estimate the radiation exposure dosage according to a statistically derived and predetermined dose-response curve. It can be used for population triage after large-scale accidental over-exposure to ionising radiation or with a view to making clinical decisions for individual patients receiving substantial radiation. In this report, we describe our experience in the establishment of a cytogenetic biodosimetry laboratory in Queen Elizabeth Hospital, Hong Kong. This was part of the contingency plan for emergency measures against radiation accidents at nuclear power stations.
Topics: Biological Assay; Chromosomes, Human; Cytogenetic Analysis; Dose-Response Relationship, Radiation; Female; Hong Kong; Humans; Male; Nuclear Power Plants; Radiation Dosage; Radiation Monitoring; Radiation, Ionizing; Radioactive Hazard Release; Radiometry; Risk Assessment
PubMed: 23535678
DOI: No ID Found -
Chemico-biological Interactions Mar 2019The goal of this manuscript is to define the role of dose rate and dose protraction on the induction of biological changes at all levels of biological organization. Both... (Review)
Review
The goal of this manuscript is to define the role of dose rate and dose protraction on the induction of biological changes at all levels of biological organization. Both total dose and the time frame over which it is delivered are important as the body has great capacity to repair all types of biological damage. The importance of dose rate has been recognized almost from the time that radiation was discovered and has been included in radiation standards as a Dose, Dose Rate, Effectiveness Factor (DDREF) and a Dose Rate Effectiveness Factor (DREF). This manuscript will evaluate the role of dose rate at the molecular, cellular, tissue, experimental animals and humans to demonstrate that dose rate is an important variable in estimating radiation cancer risk and other biological effects. The impact of low-dose rates on the Linear-No-Threshold Hypothesis (LNTH) will be reviewed since if the LNTH is not valid it is not possible to calculate a single value for a DDREF or DREF. Finally, extensive human experience is briefly reviewed to show that the radiation risks are not underestimated and that radiation at environmental levels has limited impact on total human cancer risk.
Topics: Animals; Dose-Response Relationship, Radiation; Humans; Linear Models; Models, Statistical; Neoplasms, Radiation-Induced; Radiation Dosage; Risk Assessment
PubMed: 30763551
DOI: 10.1016/j.cbi.2018.12.007 -
Journal of Medical Radiation Sciences Mar 2020On this editorial, the importance of optimisation of diagnostic imaging and radiation therapy in terms of diagnostic and therapeutic tests and treatments, education and...
On this editorial, the importance of optimisation of diagnostic imaging and radiation therapy in terms of diagnostic and therapeutic tests and treatments, education and service provision are discussed.
Topics: Humans; Practice Guidelines as Topic; Radiation Dosage; Radiology
PubMed: 32153138
DOI: 10.1002/jmrs.381 -
Cardiovascular and Interventional... Jun 2021
Topics: Humans; Radiation Dosage; Radiation Protection; Radiography, Interventional
PubMed: 33733685
DOI: 10.1007/s00270-021-02816-2 -
Journal of the American College of... Jun 2019
Topics: Heart; Heart Diseases; Humans; Lung Neoplasms; Radiation Dosage
PubMed: 31196456
DOI: 10.1016/j.jacc.2019.04.011 -
European Journal of Vascular and... Sep 2018
Topics: Prospective Studies; Radiation Dosage
PubMed: 29921532
DOI: 10.1016/j.ejvs.2018.05.029 -
European Journal of Nuclear Medicine... Feb 2019
Topics: Diagnostic Imaging; Female; Humans; Male; Radiation Dosage; Radiation Tolerance; Social Control, Formal
PubMed: 30560486
DOI: 10.1007/s00259-018-4233-7 -
Environment International Apr 2021
Topics: Radiation Dosage; Radiation, Ionizing
PubMed: 33309204
DOI: 10.1016/j.envint.2020.106286