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Current Cardiology Reviews Feb 2013Despite ample evidence that right ventricular function is a critical determinant of the clinical response to a spectrum of cardiovascular diseases, there has been only a... (Review)
Review
Despite ample evidence that right ventricular function is a critical determinant of the clinical response to a spectrum of cardiovascular diseases, there has been only a limited analysis of the unique and distinguishing physiologic properties of the RV under normal circumstances and in response to pathologic insults. This knowledge deficit is increasingly acknowledged. This review highlights some of these features and underscores the fact that rational therapy in RV failure needs to acknowledge its unique physiology and ought to be chamber specific. That is proven therapies for LV dysfunction do not necessarily apply to the RV. The updated version of this review now acknowledges recent advances in the understanding of metabolic, inflammatory and gender-specific influences on the right ventricle.
Topics: Heart Ventricles; Humans; Hypertension, Pulmonary; Sex Factors; Ventricular Dysfunction, Right; Ventricular Function, Right
PubMed: 23092273
DOI: 10.2174/157340313805076296 -
JACC. Cardiovascular Imaging Jun 2020
Topics: Cardiomyopathies; Heart Ventricles; Humans; Magnetic Resonance Imaging; Sarcoidosis
PubMed: 32307252
DOI: 10.1016/j.jcmg.2020.02.017 -
The Canadian Journal of Cardiology Jul 2015
Topics: Continuous Positive Airway Pressure; Female; Heart Ventricles; Humans; Male; Sleep Apnea, Obstructive; Ultrasonography; Ventricular Function, Right
PubMed: 26112298
DOI: 10.1016/j.cjca.2015.02.035 -
The Journal of Thoracic and... Jun 2022
Topics: Decompression; Heart Defects, Congenital; Heart Ventricles; Humans; Pulmonary Atresia; Ventricular Septum
PubMed: 34620505
DOI: 10.1016/j.jtcvs.2021.08.083 -
Journal of Cardiothoracic and Vascular... Jun 2021
Topics: COVID-19; Heart Ventricles; Humans; Lung Injury; SARS-CoV-2; Ventricular Dysfunction, Right
PubMed: 33546967
DOI: 10.1053/j.jvca.2021.01.014 -
The Journal of Thoracic and... Aug 2017
Topics: Double Outlet Right Ventricle; Heart Ventricles; Humans
PubMed: 28477947
DOI: 10.1016/j.jtcvs.2017.04.006 -
Current Cardiology Reviews 2015Pulmonary arterial hypertension (PAH) is a panvasculopathy that affects the distal pulmonary arteries and leads to restricted blood flow. This increased afterload leads... (Review)
Review
Pulmonary arterial hypertension (PAH) is a panvasculopathy that affects the distal pulmonary arteries and leads to restricted blood flow. This increased afterload leads to adaptive mechanisms of the right ventricle, with eventual failure once it can no longer compensate. Pulmonary hypertension from associated conditions, most importantly left heart disease, i.e. heart failure, can also lead to the same sequela. Patients often experience early vague symptoms of dyspnea and exercise intolerance, and thus PH can elude clinicians until right heart failure symptoms predominate. Evidence-based treatment options with pulmonary vasodilators are available for those with PAH and should be employed early. It is essential that patients be accurately categorized by their etiology of PH, as treatment strategies differ, and can potentially be dangerous if employed in the wrong clinical scenario.
Topics: Heart Failure; Heart Ventricles; Humans; Hypertension, Pulmonary; World Health Organization
PubMed: 24251459
DOI: 10.2174/1573403x09666131117164122 -
Arquivos Brasileiros de Cardiologia Dec 2022
Topics: Humans; Heart Ventricles; Wolff-Parkinson-White Syndrome; Mutation; AMP-Activated Protein Kinases
PubMed: 36541985
DOI: 10.36660/abc.20220795 -
BMJ Case Reports May 2014A full-term female baby, a product of non-consanguineous marriage, was born at 37 weeks of gestation with a birth weight of 2.08 kg. Antenatal scan at 31 weeks...
A full-term female baby, a product of non-consanguineous marriage, was born at 37 weeks of gestation with a birth weight of 2.08 kg. Antenatal scan at 31 weeks revealed complex congenital heart disease with a hypoplastic right ventricle, pulmonary atresia and an intact septum. Immediately after birth, the infant was shifted to the nursery and was started on intravenous fluids and infusion prostaglandin E1 (Alprostidil). On examination, she had microcephaly, periorbital puffiness, a long philtrum, a broad nasal bridge and retrognathia, up slanting palpebral fissures, widely spaced nipples, a sacral dimple and right upper limb postaxial polydactyly. Postnatal echocardiography confirmed a large ostium secundum atrial septal defect with left to right shunt, right ventricle hypoplasia, pulmonary atresia with an intact septum and a large vertical patent ductus arteriosus. Ophthalmological examination showed a bilateral chorioretinal coloboma sparing disc and fovea. Karyotyping showed an extra small marker chromosome suggestive of the Cat eye syndrome.
Topics: Abnormalities, Multiple; Aneuploidy; Birth Weight; Chromosome Disorders; Chromosomes, Human, Pair 22; Ductus Arteriosus, Patent; Eye Abnormalities; Fatal Outcome; Female; Heart Defects, Congenital; Heart Septal Defects, Atrial; Heart Ventricles; Humans; Infant, Newborn; Microcephaly; Monitoring, Physiologic; Term Birth; Ultrasonography
PubMed: 24842361
DOI: 10.1136/bcr-2014-203923 -
BioMed Research International 2018
Topics: Animals; Heart Ventricles; Humans
PubMed: 29862260
DOI: 10.1155/2018/2868437