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Saudi Medical Journal Aug 2018Heterotopic pancreas is defined as aberrantly located pancreatic tissue without anatomical, vascular, or neural connection to the pancreas. Usual sites include the...
Heterotopic pancreas is defined as aberrantly located pancreatic tissue without anatomical, vascular, or neural connection to the pancreas. Usual sites include the stomach, duodenum, jejunum, and spleen; in rare cases, heterotopic pancreas can be found in the lungs, gallbladder, Meckel's diverticulum, and the mediastinum. In most cases, it is an insignificant, incidental finding. Pre-operative diagnosis is not possible, and histopathological examination is mandatory for establishing a definite diagnosis. Less than 40 cases of heterotopic pancreas in the gallbladder have been reported worldwide. Recently, a laparoscopic cholecystectomy specimen from a 43-year-old male showed a small nodule in the gallbladder neck. Microscopy revealed heterotopic pancreas composed of exocrine and endocrine glandular tissue with ducts. We report this case to highlight this rare, incidental finding. This condition should not cause pathologists to over diagnose such occurrences as malignancies; neither should they be neglected because they have potential complications.
Topics: Adult; Choristoma; Diagnosis, Differential; Gallbladder Diseases; Humans; Male; Pancreas
PubMed: 30106423
DOI: 10.15537/smj.2018.8.22602 -
Proceedings of the Royal Society of... Jul 1929
PubMed: 19987080
DOI: No ID Found -
The Indian Journal of Surgery Oct 2016Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the GI tract, they have a wide spectrum of clinical manifestations, and a small...
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the GI tract, they have a wide spectrum of clinical manifestations, and a small proportion of them present as an acute abdomen due to obstruction, perforation, or hemoperitoneum. We present a case of a perforated GIST of the Meckel's diverticulum and review the current literature on perforated GISTs. We ran a search on Pubmed and Google Scholar with the following terms "perforated GIST," "perforated Meckel's diverticulum," "GIST with peritonitis," and "GIST in Meckel's diverticulum." After selecting the relevant articles, we tabulated our results and analyzed the data. Out of the 45 cases, 32 (71.1 %) were male and 13 (28.8 %) were female. Out of the 45 reported cases, 41 (91.1 %) were from the small intestine, 2 (4.44 %) cases from the stomach, and 2 (4.44 %) from the small bowel. In 15 (33.33 %) cases, the site of perforation was the Meckel's diverticulum (MD). Forty-year-old male, presented with features of peritonitis localized to the right iliac fossa, was diagnosed as acute appendicitis and subjected to a diagnostic laparoscopy. Intraoperatively, a perforated Meckel's diverticulum was found, which on histopathological examination contained a low-grade GIST. Our literature search revealed that in reported cases of perforated GISTs, there is a slight male preponderance. Small bowel appears to be the most common site for a perforated GIST, and a significant proportion (30.23 %) arise from the Meckel's diverticulum. And most importantly, the commonest tumor to cause perforation of a Meckel's diverticulum is a GIST.
PubMed: 27994335
DOI: 10.1007/s12262-016-1525-7 -
Journal of Surgical Case Reports Mar 2022Heterotropic pancreatic tissue is a rare entity where aberrant pancreatic tissue is located without any anatomical connection to the pancreas. It is usually reported to...
Heterotropic pancreatic tissue is a rare entity where aberrant pancreatic tissue is located without any anatomical connection to the pancreas. It is usually reported to be found in stomach, duodenum, jejunum and spleen. Rare locations include lung, mediastinum, liver, mesentery, ileum, meckels diverticulum and gallbladder [1, 2]. This anomaly is often an incidental finding during laparotomy or autopsy. We describe a case of an elective laparoscopic cholecystectomy with the histology of the gallbladder showing focal ectopic pancreatic acinar tissue.
PubMed: 35350216
DOI: 10.1093/jscr/rjac098 -
Gut Dec 1969Microbial populations of the small bowel and bile salt metabolism were studied in 15 patients with lesions of the stomach and small intestine. These types of...
Microbial populations of the small bowel and bile salt metabolism were studied in 15 patients with lesions of the stomach and small intestine. These types of microorganism could be correlated with the site and extent of stasis in the small bowel and the presence of a normally functioning stomach. The presence of obligate anaerobes (bacteroides) and free bile acids could be correlated with areas of stagnation. When these abnormalities were detected throughout the small bowel, steatorrhoea was also noted. However, bacteroides and free bile acids in localized regions of either proximal or distal small bowel were generally associated with normal faecal fat excretion. Vitamin B(12) malabsorption appeared to be related to the total number of bacteria colonizing the small bowel rather than to any specific type of microorganisms. The effect of antibiotics on intestinal function and bacteriology was studied in three patients. In one patient, the broad-spectrum antibiotic tetracycline was effective in eradicating an abnormal bacterial flora. In the other two, lincomycin, which is specifically effective in eradicating the anaerobic flora, restored intestinal function to normal.
Topics: Adult; Aged; Bacteria; Bacteroides; Bile Acids and Salts; Celiac Disease; Diverticulum; Fats; Feces; Female; Gastrectomy; Humans; Intestinal Absorption; Intestinal Diseases; Intestine, Small; Lincomycin; Lipids; Male; Middle Aged; Stomach Diseases; Tetracycline; Vitamin B 12
PubMed: 4983639
DOI: 10.1136/gut.10.12.963 -
Canadian Medical Association Journal Jul 1966Between 1947 and 1964, 32 infants in the first two weeks of life were seen at The Hospital for Sick Children, Toronto, with radiological evidence of free air in the...
Between 1947 and 1964, 32 infants in the first two weeks of life were seen at The Hospital for Sick Children, Toronto, with radiological evidence of free air in the peritoneal cavity. The clinical picture and the radiological signs in these infants are described. Perforations were found at all levels of the gastrointestinal tract. The overall mortality rate was 59%. The stomach was the most common site of perforation; it occurred in 11 children, of whom five survived. Prompt surgery was essential for survival, but when immediate laparotomy is not practical, abdominal paracentesis may prove to be life-saving.
Topics: Drainage; Duodenum; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Perforation; Intestine, Large; Intestine, Small; Laparotomy; Meckel Diverticulum; Pneumoperitoneum; Radiography; Stomach
PubMed: 5947764
DOI: No ID Found -
The Pan African Medical Journal 2019Gastric diverticula are the most uncommon form of gastrointestinal diverticula. They can either be of true or false type with different pathogenesis. They may be very...
Gastric diverticula are the most uncommon form of gastrointestinal diverticula. They can either be of true or false type with different pathogenesis. They may be very challenging to diagnose as symptoms are nonspecific and imaging can simulate a malignant lesion. We report an unusual case of pre-pyloric diverticulum in a 69-year-old man, leading to severe gastric obstruction with a poor general condition. As subsequent endoscopy and imaging were alarming and couldn't exclude malignancy, the patient underwent an antrectomy. The final diagnosis was made on pathological examination. We discuss, through this case, the clinical and pathological features of gastric diverticula with an emphasis on the pathogenesis of this rare entity and the risk of a malignant transformation.
Topics: Aged; Diverticulum, Stomach; Gastrectomy; Humans; Male; Stomach Neoplasms
PubMed: 31223371
DOI: 10.11604/pamj.2019.32.80.18075 -
World Journal of Gastroenterology Sep 2013Gastric diverticula are rare and uncommon conditions. Most gastric diverticula are asymptomatic. When symptoms arise, they are most commonly upper abdominal pain, nausea... (Review)
Review
Gastric diverticula are rare and uncommon conditions. Most gastric diverticula are asymptomatic. When symptoms arise, they are most commonly upper abdominal pain, nausea and emesis, while dyspepsia and vomiting are less common. Occasionally, patients with gastric diverticula can have dramatic presentations related to massive bleeding or perforation. The diagnosis may be difficult, as symptoms can be caused by more common gastrointestinal pathologies and only aggravated by diverticula. The appropriate management of diverticula depends mainly on the symptom pattern and as well as diverticulum size. There is no specific therapeutic strategy for an asymptomatic diverticulum. Although some authors support conservative therapy with antacids, this provides only temporary symptom relief since it is not able to resolve the underlying pathology. Surgical resection is the mainstay of treatment when the diverticulum is large, symptomatic or complicated by bleeding, perforation or malignancy, with over two-thirds of patients remaining symptom-free after surgery, while laparoscopic resection, combined with intraoperative endoscopy, is a safe and feasible approach with excellent outcomes. Here, we present two cases of uncommon large symptomatic gastric diverticula with a discussion of the cornerstones in management and report a minimally invasive solution, with a brief review of the literature.
Topics: Abdominal Pain; Diverticulum, Stomach; Endoscopy, Gastrointestinal; Female; Humans; Laparoscopy; Middle Aged; Surgical Stapling; Treatment Outcome
PubMed: 24106415
DOI: 10.3748/wjg.v19.i36.6114 -
BMJ Case Reports Apr 2019We describe the case of an 82-year-old Caucasian woman who presented to our institution as a transfer from an outside hospital with nausea, vomiting and abdominal pain...
We describe the case of an 82-year-old Caucasian woman who presented to our institution as a transfer from an outside hospital with nausea, vomiting and abdominal pain with CT imaging concerning for a duodenal mass or abscess in the juxtapapillary region of the second part of the duodenum. Upper endoscopy showed a non-bleeding duodenal diverticulum with purulent discharge consistent with diverticulitis. She underwent endoscopic disimpaction with irrigation and received a 14 day course of antibiotics, after which she presented for follow-up 1 month after discharge without complications. This case highlights the rarity of juxtapapillary duodenal diverticulitis, its nonspecific clinical presentation and imaging findings and the importance of early diagnosis and management to prevent severe complications including perforation.
Topics: Abdominal Pain; Aged, 80 and over; Anti-Bacterial Agents; Diverticulitis; Duodenal Diseases; Endoscopy; Female; Humans; Nausea; Therapeutic Irrigation; Tomography, X-Ray Computed; Treatment Outcome; Vomiting
PubMed: 30981989
DOI: 10.1136/bcr-2019-229259 -
Cureus Nov 2022Gastrointestinal duplications can be found in all parts of the gastrointestinal tract. Duplications of the stomach comprise 2-8% of all duplications and are mostly...
Gastrointestinal duplications can be found in all parts of the gastrointestinal tract. Duplications of the stomach comprise 2-8% of all duplications and are mostly diagnosed during the first year of life. We present a case of a gastric duplication cyst in a 29-year-old female, presenting with epigastric pain and vomiting. Preoperative diagnosis was assumed to be pyloric stenosis. Intraoperatively, a large mass that was attached to the greater curvature was found. Histopathology results were consistent with gastric duplication cyst.
PubMed: 36505143
DOI: 10.7759/cureus.31199