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BMJ (Clinical Research Ed.) Sep 1989
Topics: Abortion, Criminal; Abortion, Induced; Abortion, Therapeutic; Adolescent; Australia; Embryo, Mammalian; Embryonic and Fetal Development; Financial Support; France; Human Experimentation; Humans; International Cooperation; Internationality; Italy; Jurisprudence; Legislation as Topic; Minors; Parental Consent; Physicians; Politics; Public Policy; Socioeconomic Factors; Spain; Statistics as Topic; Third-Party Consent; United Kingdom
PubMed: 11644419
DOI: No ID Found -
Canadian Medical Association Journal Oct 1972
Topics: Abortion, Therapeutic; Contraceptives, Oral; Female; Humans; Pregnancy
PubMed: 4638845
DOI: No ID Found -
CMAJ : Canadian Medical Association... Jan 1990
Topics: Abortion, Induced; Abortion, Therapeutic; Attitude of Health Personnel; Female; Humans; Pregnancy
PubMed: 2295039
DOI: No ID Found -
British Medical Journal Dec 1973
Topics: Abortion, Therapeutic; Adolescent; Adult; Female; Glucose Tolerance Test; Humans; Pregnancy; Pregnancy in Diabetics
PubMed: 4758565
DOI: 10.1136/bmj.4.5893.678 -
California Medicine Dec 1970
Topics: Abortion, Therapeutic; Erythroblastosis, Fetal; Female; Humans; Immunoglobulins; Infant, Newborn; Pregnancy; Rh-Hr Blood-Group System; gamma-Globulins
PubMed: 4098761
DOI: No ID Found -
California Medicine Oct 1969
Topics: Abortion, Therapeutic; Female; Humans; Mental Health; Pregnancy; Psychology
PubMed: 5347206
DOI: No ID Found -
British Medical Journal Nov 1965
Topics: Abortion, Therapeutic; Adult; Contraception; Family Planning Services; Female; Humans; Infant Mortality; Maternal Mortality; Scotland; Statistics as Topic; Sterilization, Reproductive
PubMed: 5833617
DOI: 10.1136/bmj.2.5471.1141 -
CMAJ : Canadian Medical Association... Mar 2013
Review
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Acne Vulgaris; Adult; Female; Humans; Isotretinoin; Patient Education as Topic; Pregnancy; Pregnancy, High-Risk; Risk Assessment; Teratogens
PubMed: 23296582
DOI: 10.1503/cmaj.120729 -
Breast Cancer Research : BCR 2006BRCA1 and BRCA2 mutation carriers are at increased risk for developing both breast and ovarian cancer. It has been suggested that carriers of BRCA1/2 mutations may also... (Comparative Study)
Comparative Study
INTRODUCTION
BRCA1 and BRCA2 mutation carriers are at increased risk for developing both breast and ovarian cancer. It has been suggested that carriers of BRCA1/2 mutations may also be at increased risk of having recurrent (three or more) miscarriages. Several reproductive factors have been shown to influence the risk of breast cancer in mutation carriers, but the effects of spontaneous and therapeutic abortions on the risk of hereditary breast cancer risk have not been well studied to date.
METHODS
In a matched case-control study, the frequencies of spontaneous abortions were compared among 1,878 BRCA1 mutation carriers, 950 BRCA2 mutation carriers and 657 related non-carrier controls. The rates of spontaneous and therapeutic abortions were compared for carriers with and without breast cancer.
RESULTS
There was no difference in the rate of spontaneous abortions between carriers of BRCA1 or BRCA2 mutations and non-carriers. The number of spontaneous abortions was not associated with breast cancer risk among BRCA1 or BRCA2 mutation carriers. However, BRCA2 carriers who had two or more therapeutic abortions faced a 64% decrease in the risk of breast cancer (odds ratio = 0.36; 95% confidence interval 0.16-0.83; p = 0.02).
CONCLUSION
Carrying a BRCA1 or BRCA2 mutation is not a risk factor for spontaneous abortions and spontaneous abortions do not appear to influence the risk of breast cancer in carriers of BRCA1 or BRCA2 mutations. However, having two or more therapeutic abortions may be associated with a lowered risk of breast cancer among BRCA2 carriers.
Topics: Abortion, Spontaneous; Abortion, Therapeutic; Breast Neoplasms; Case-Control Studies; Female; Genes, BRCA1; Genes, BRCA2; Genetic Carrier Screening; Humans; Mutation; Pregnancy; Risk Assessment; Risk Factors
PubMed: 16563180
DOI: 10.1186/bcr1387 -
British Medical Journal Jun 1969
Topics: Abortion, Therapeutic; Erythroblastosis, Fetal; Female; Humans; Infant, Newborn; Pregnancy; Rh-Hr Blood-Group System
PubMed: 4977717
DOI: 10.1136/bmj.2.5659.759-a