Disease or Syndrome
Guillain-Barre syndrome
Subclass of:
Peripheral Nervous System Diseases;
Polyradiculoneuropathy
Also called:
Acute idiopathic polyneuritis; Acute inflammatory polyneuropathy; Infectious polyneuritis; Landry-Guillain-Barre syndrome; Guillain-Barre's Syndrome
Definitions related to guillain-barre syndrome:
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(guillain-barr� syndrome) A clinically heterogeneous spectrum of rare post-infectious neuropathies that usually occur in otherwise healthy patients and encompasses acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), Miller-Fisher syndrome (MFS) and some other regional variants.OrphaNetINSERM, 2021
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A progressive autoimmune disorder of the peripheral nervous system characterized by respiratory insufficiency, limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A rapidly progressive autoimmune disorder of the peripheral nervous system characterized by limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face.NCI ThesaurusU.S. National Cancer Institute, 2021
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An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Guillain-Barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system (PNS). The PNS nerves connect your brain and spinal cord with the rest of your body. Damage to these nerves makes it hard for them to transmit signals. As a result, your muscles have trouble responding to your brain. No one knows what causes the syndrome. Sometimes it is triggered by an infection, surgery, or a vaccination. The first symptom is usually weakness or a tingling feeling in your legs. The feeling can spread to your upper body. In severe cases, you become almost paralyzed. This is life-threatening. You might need a respirator to breathe. Symptoms usually worsen over a period of weeks and then stabilize. Guillain-Barre can be hard to diagnose. Possible tests include nerve tests and a spinal tap. Most people recover. Recovery can take a few weeks to a few years. Treatment can help symptoms, and may include medicines or a procedure called plasma exchange. NIH: National Institute of Neurological Disorders and StrokeMedlinePlusU.S. National Library of Medicine, 2021
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(guillain barre syndrome) Progressive ascending motor neuron paralysis of unknown etiology, frequently following an enteric or respiratory infection.CRISP ThesaurusNational Institutes of Health, 2006
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A disorder characterized by the body's immune system attacking the peripheral nervous system causing ascending paralysis.Common Terminology Criteria for Adverse EventsU.S. National Institutes of Health, 2021
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Guillain-Barr� syndrome is an acute, usually rapidly progressive but self-limited inflammatory polyneuropathy characterized by muscular weakness and mild distal sensory loss. Cause is thought to be autoimmune. Diagnosis is clinical. Treatment includes IV immune globulin, plasma exchange, and, for severe cases, mechanical ventilation.Merck & Co., Inc., 2020
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Guillain-Barr� syndrome (GBS) can be described as a collection of clinical syndromes that manifests as an acute inflammatory polyradiculoneuropathy with resultant weakness and diminished reflexes. With poliomyelitis under control in developed countries, GBS is now the most important cause of acute flaccid paralysis.WebMD, 2019
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Guillain-Barre (gee-YAH-buh-RAY) syndrome is a rare disorder in which your body's immune system attacks your nerves. Weakness and tingling in your extremities are usually the first symptoms.Mayo Foundation for Medical Education and Research
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Guillain-Barre syndrome (GBS) is a rare syndrome in which the body�s immune system attacks part of the peripheral nervous system. The peripheral nervous system carries signals from the brain to the muscles. Symptoms of GBS include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot...National Center for Advancing Translational Sciences
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Guillain-Barre syndrome (GBS) is a type of acute inflammatory neuropathy. It is a clinically defined syndrome characterized by motor difficulty, absence of deep tendon reflexes, paresthesias without objective sensory loss, and increased CSF albumin with absence of cellular reaction (albuminocytologic dissociation). Acute inflammatory...Athenahealth, Inc., 2019
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