Antibiotic
cefotaxime
Brand Names:
Claforan
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Acinetobacter Infections;
Bacteroides Infections;
Bone Diseases, Infectious;
Clostridium Infections;
Escherichia coli Infections;
Fusobacterium Infections;
Gonorrhea;
Haemophilus Infections;
Klebsiella Infections;
Meningitis, Bacterial;
Pelvic Inflammatory Disease;
Peritonitis;
Pneumonia, Bacterial;
Proteus Infections;
Pseudomonas Infections;
Salmonella Infections;
Sepsis;
Serratia Infections;
Skin Diseases, Bacterial;
Soft Tissue Infections;
Staphylococcal Infections;
Streptococcal Infections;
Urinary Tract Infections
More Information:
Definitions related to cefotaxime:
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A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.NCI ThesaurusU.S. National Cancer Institute, 2021
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Semisynthetic broad-spectrum cephalosporin.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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