Pharmacologic Substance
cholinesterase inhibitor
cho·lin·es·ter·ase in·hib·i·tor
Subclass of:
Cholinergic Agents;
Enzyme Inhibitors
Definitions related to cholinesterase inhibitors:
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Any substance or agent which suppresses, prevents or opposes the action of cholinesterase resulting in the potentiation of the action of endogenously released acetylcholine at cholinergic synapses; cholinesterase inhibition is associated with a variety of acute symptoms such as nausea, vomiting, blurred vision, stomach cramps, and rapid heart rate.CRISP ThesaurusNational Institutes of Health, 2006
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Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Anticholinesterase, any of several drugs that prevent destruction of the neurotransmitter acetylcholine by the enzyme acetylcholinesterase within the nervous system. Acetylcholine acts to transmit nerve impulses within the parasympathetic nervous system--i.e., that part of the autonomic nervous...Encyclopedia Britannica, Inc., 2020
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