Disease or Syndrome
muscular dystrophy
mus·cu·lar dys·tro·phy
Subclass of:
Muscular Disorders, Atrophic;
Genetic Diseases, Inborn
Also called:
MD
Definitions related to muscular dystrophy:
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A group of inherited progressive muscle disorders characterized by muscle weakness and eventual death of the muscle tissues. Examples include Duchenne muscular dystrophy, Becker's muscular dystrophy, Emery-Dreifuss muscular dystrophy, facioscapulohumeral muscular dystrophy, and limb-girdle muscular dystrophy.NCI ThesaurusU.S. National Cancer Institute, 2021
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General term for a group of inherited disorders which are characterized by progressive degeneration of skeletal muscles.CRISP ThesaurusNational Institutes of Health, 2006
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Muscular dystrophy (MD) is a group of more than 30 inherited diseases. They all cause muscle weakness and muscle loss. Some forms of MD appear in infancy or childhood. Others may not appear until middle age or later. The different types can vary in whom they affect, which muscles they affect, and what the symptoms are. All forms of MD grow worse as the person's muscles get weaker. Most people with MD eventually lose the ability to walk. There is no cure for muscular dystrophy. Treatments can help with the symptoms and prevent complications. They include physical and speech therapy, orthopedic devices, surgery, and medications. Some people with MD have mild cases that worsen slowly. Others cases are disabling and severe. NIH: National Institute of Neurological Disorders and StrokeMedlinePlusU.S. National Library of Medicine, 2021
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The term dystrophy means abnormal growth. However, muscular dystrophy is used to describe primary myopathies with a genetic basis and a progressive course characterized by progressive skeletal muscle weakness and wasting, defects in muscle proteins, and histological features of muscle fiber degeneration (necrosis) and regeneration. If possible, it is preferred to use other HPO terms to describe the precise phenotypic abnormalities.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(muscular dystrophies) A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Muscular dystrophy (MD) is a collective group of inherited noninflammatory but progressive muscle disorders without a central or peripheral nerve abnormality. The disease affects the muscles with definite fiber degeneration but without evidence of morphologic aberrations.WebMD, 2019
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Muscular dystrophy is a group of diseases that cause progressive weakness and loss of muscle mass. In muscular dystrophy, abnormal genes (mutations) interfere with the production of proteins needed to form healthy muscle.Mayo Foundation for Medical Education and Research
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Muscular dystrophy (MD) refers to a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. Some forms of MD are seen in newborns, infants or children, while others have late-onset and may not appear until middle age or later. The disorders differ in...National Center for Advancing Translational Sciences
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Muscular dystrophies are progressive, generalized diseases of muscle, most often caused by defective or specifically absent glycoproteins (e.g., dystrophin) in the muscle membrane. All muscular dystrophies are characterized by ongoing degeneration and regeneration of muscle fibers. The most common and rapidly progressive muscular...Athenahealth, Inc., 2019
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Muscular dystrophy, hereditary disease that causes progressive weakness and degeneration of the skeletal muscles. Of the several types of muscular dystrophy, the more common are Duchenne, facioscapulohumeral, Becker, limb-girdle, and myotonic dystrophy. In all of these there is usually early...Encyclopedia Britannica, Inc., 2020
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