Neoplastic Process
seminoma
[ seh-mih-noh-muh ]
Subclass of:
Germinoma
Definitions related to seminoma:
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(seminoma, malignant) A malignant germ cell neoplasm of the testis.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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A germinomatous germ cell tumor originating in the testis.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A radiosensitive malignant germ cell tumor found in the testis (especially undescended), and extragonadal sites (anterior mediastinum and pineal gland). It is characterized by the presence of uniform cells with clear or dense cytoplasm which contains glycogen, and by a large nucleus which contains one or more nucleoli. The neoplastic germ cells form aggregates separated by fibrous septa. The fibrous septa contain chronic inflammatory cells, mainly lymphocytes.NCI ThesaurusU.S. National Cancer Institute, 2021
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A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A type of cancer of the testicles. Seminomas may spread to the lung, bone, liver, or brain.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(testicular seminoma) A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.NCI ThesaurusU.S. National Cancer Institute, 2021
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(testicular seminoma) The presence of a seminoma, an undifferentiated germ cell tumor of the testis.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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The study of testicular germ cell tumors (GCTs) is a unique area of urologic oncology, as treatment algorithms have benefited from numerous randomized prospective clinical trials (unlike prostate cancer) and because metastatic disease is highly responsive to multimodal treatment (unlike renal cell carcinoma). Seminoma is a histologic...WebMD, 2019
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Testicular seminomatous germ cell tumor is a rare testicular germ cell tumor (see this term), most commonly presenting with a painless mass in the scrotum, with a very high cure rate if caught in the early stages.National Center for Advancing Translational Sciences
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