Disease or Syndrome
Evans syndrome
Definitions related to evans syndrome:
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A rare chronic hematologic disorder characterized by the simultaneous or sequential association of autoimmune hemolytic anemia (AIHA; a disorder in which auto-antibodies are directed against red blood cells causing anemia of varying degrees of severity) with immune thrombocytopenic purpura (ITP; a coagulation disorder in which auto-antibodies are directed against platelets causing hemorrhagic episodes) and occasionally autoimmune neutropenia, in the absence of a known underlying etiology.OrphaNetINSERM, 2021
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A rare, chronic and relapsing autoimmune disorder of unknown etiology, characterized by the presence of immune thrombocytopenia and autoimmune hemolytic anemia.NCI ThesaurusU.S. National Cancer Institute, 2021
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An autoimmune disorder of unknown etiology that is characterized by the presence of immune thrombocytopenia and autoimmune hemolytic anemia.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Evans syndrome is the coexistence of simultaneous or sequential direct Coombs-positive autoimmune hemolytic anemia (AIHA) with immune-mediated thrombocytopenia. In the initial description by Evans et al in 1951, the anemia and thrombocytopenia varied with respect to time of onset, course, and duration.WebMD, 2019
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Evans syndrome is a very rare autoimmune disorder in which the immune system destroys the body's red blood cells, white blood cells and/or platelets. Affected people often experience thrombocytopenia (too few platelets) and Coombs' positive hemolytic anemia (premature destruction of red blood cells). Signs and symptoms may include...National Center for Advancing Translational Sciences
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