Disease or Syndrome
Hashimoto disease
[ hah-shee-moh-toh dih-zeez ]
Subclass of:
Autoimmune thyroiditis
Also called:
Autoimmune Thyroiditis; Chronic Lymphocytic Thyroiditis; Hashimoto's Thyroiditis
Definitions related to hashimoto disease:
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An autoimmune condition of the thyroid gland (a gland located beneath the larynx). It is caused by the formation of antibodies that attack the thyroid gland and it usually causes hypothyroidism (too little thyroid hormone). Symptoms include fatigue, weight gain, constipation, dry skin, depression, and the inability to exercise. It is more common in females and can run in families.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Hashimoto thyroiditis is a condition that affects the function of the thyroid, which is a butterfly-shaped gland in the lower neck. The thyroid makes hormones that help regulate a wide variety of critical body functions. For example, thyroid hormones influence growth and development, body temperature, heart rate, menstrual cycles, and weight. Hashimoto thyroiditis is a form of chronic inflammation that can damage the thyroid, reducing its ability to produce hormones. One of the first signs of Hashimoto thyroiditis is an enlargement of the thyroid called a goiter. Depending on its size, the enlarged thyroid can cause the neck to look swollen and may interfere with breathing and swallowing. As damage to the thyroid continues, the gland can shrink over a period of years and the goiter may eventually disappear. Other signs and symptoms resulting from an underactive thyroid can include excessive tiredness (fatigue), weight gain or difficulty losing weight, hair that is thin and dry, a slow heart rate, joint or muscle pain, and constipation. People with this condition may also have a pale, puffy face and feel cold even when others around them are warm. Affected women can have heavy or irregular menstrual periods and difficulty conceiving a child (impaired fertility). Difficulty concentrating and depression can also be signs of a shortage of thyroid hormones. Hashimoto thyroiditis usually appears in mid-adulthood, although it can occur earlier or later in life. Its signs...MedlinePlus GeneticsU.S. National Library of Medicine, 2021
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(hashimoto thyroiditis) A chronic, autoimmune type of thyroiditis associated with hypothyroidism.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(hashimoto thyroiditis) An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism.NCI ThesaurusU.S. National Cancer Institute, 2021
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(hashimoto thyroiditis) An autoimmune disorder characterized by inflammation and lymphocytic infiltration of the thyroid gland, sometimes associated with reduced thyroid function.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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(hashimoto's thyroiditis) A disease in which the body's immune system prevents the thyroid gland from producing enough thyroid hormone.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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(lymphomatous thyroiditis) Progressive enlargement of the thyroid gland, often associated with hypothyroidism.CRISP ThesaurusNational Institutes of Health, 2006
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Hashimoto thyroiditis is chronic autoimmune inflammation of the thyroid with lymphocytic infiltration. Findings include painless thyroid enlargement and symptoms of hypothyroidism. Diagnosis involves demonstration of high titers of thyroid peroxidase antibodies. Lifelong L-thyroxine replacement is typically required.Merck & Co., Inc., 2020
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Hashimoto thyroiditis is part of the spectrum of autoimmune thyroid diseases (AITDs) and is characterized by the destruction of thyroid cells by various cell- and antibody-mediated immune processes. This condition is the most common cause of hypothyroidism in the United States in individuals older than 6 years.WebMD, 2019
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Hashimoto's disease is a condition in which your immune system attacks your thyroid, a small gland at the base of your neck below your Adam's apple. The thyroid gland is part of your endocrine system, which produces hormones that coordinate many of your body's functions.Mayo Foundation for Medical Education and Research
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Hashimoto�s syndrome is an autoimmune disease in which a person's immune system mistakenly attacks the thyroid gland, reducing its ability to produce hormones (hypothyroidism). Many people with Hashimoto�s syndrome have no symptoms at first. An early sign of the syndrome may be enlargement of the thyroid (called a goiter), which can...National Center for Advancing Translational Sciences
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Hashimoto disease, a noninfectious form of inflammation of the thyroid gland (thyroiditis). Hashimoto disease is an autoimmune disorder (i.e., the body reacts to its own tissues as though they were foreign substances). Its onset is insidious, with gradual enlargement of the thyroid gland (a...Encyclopedia Britannica, Inc., 2020
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