Neoplastic Process
Kaposi's sarcoma
Ka·po·si's sar·co·ma [ kuh-poh-seez, kap-uh- ]
Subclass of:
Neoplasms, Vascular Tissue;
Herpesviridae Infections;
Sarcoma
Also called:
Kaposi's Sarcoma; KS; Multiple Idiopathic Hemorrhagic Sarcoma
Definitions related to kaposi sarcoma:
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A malignant neoplasm characterized by a vascular proliferation which usually contains blunt endothelial cells. Erythrocyte extravasation and hemosiderin deposition are frequently present. The most frequent site of involvement is the skin; however it may also occur internally. It generally develops in people with compromised immune systems including those with acquired immune deficiency syndrome (AIDS).NCI ThesaurusU.S. National Cancer Institute, 2021
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Kaposi sarcoma (KS) is a cancer that causes patches of abnormal tissue to grow under the skin, in the lining of the mouth, nose, and throat, in lymph nodes, or in other organs. These patches, or lesions, are usually red or purple. They are made of cancer cells, blood vessels, and blood cells. KS is caused by infection with human herpesvirus-8 (HHV-8). Most people infected with HHV-8 don't get KS. It usually happens in People with weak immune systems, due to HIV/AIDS, drugs taken after an organ transplant, or another disease; Older men of Jewish or Mediterranean descent; Young men in Africa. The skin lesions may not cause symptoms. But they can spread to other parts of the body, especially in people with HIV/AIDS. If they spread to the digestive tract or lungs, they can cause bleeding. Lesions on the lungs can also make it hard to breathe. Treatment depends on where the lesions are and how bad they are. Options include radiation therapy, surgery, chemotherapy, and biologic therapy. People with HIV/AIDS also take HIV/AIDS medicines. NIH: National Cancer InstituteMedlinePlusU.S. National Library of Medicine, 2021
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(sarcoma, kaposi) A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(kaposi's sarcoma) A systemic disease which can present with cutaneous lesions with or without internal involvement. Tumors are caused by Human herpesvirus 8 (HHV8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV).Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(kaposi's sarcoma) A type of cancer characterized by the abnormal growth of blood vessels that develop into skin lesions or occur internally.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(kaposi's sarcoma) Multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas; occurs spontaneously in Jewish and Italian males; aggressive variant in young children is endemic in some areas of Africa; a third form occurs in about 0.04% of kidney transplant patients; there is also a high incidence in AIDS patients; human herpesvirus 8 is the suspected cause.CRISP ThesaurusNational Institutes of Health, 2006
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Kaposi sarcoma is a multicentric vascular tumor caused by herpesvirus type 8. It can occur in classic, AIDS-associated, endemic (in Africa), and iatrogenic (eg, after organ transplantation) forms. Diagnosis is by biopsy. Treatment for indolent superficial lesions involves cryotherapy, electrocoagulation, excision, or electron beam...Merck & Co., Inc., 2020
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Frequency United States Before the AIDS epidemic, Kaposi sarcoma (Kaposi's sarcoma, KS) was rare. It was one of the earliest clinical presentations seen in the AIDS epidemic.WebMD, 2019
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Kaposi's sarcoma is a type of cancer that forms in the lining of blood and lymph vessels. The tumors (lesions) of Kaposi's sarcoma typically appear as painless purplish spots on the legs, feet or face. Lesions can also appear in the genital area, mouth or lymph nodes. In severe Kaposi's sarcoma, lesions may develop in the digestive tract...Mayo Foundation for Medical Education and Research
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Kaposi sarcoma (KS) is a cancer that develops from the cells that line lymph or blood vessels. It usually appears as tumors on the skin or on mucosal surfaces such as inside the mouth, but tumors can also develop in other parts of the body (including the lymph nodes, lungs, or digestive tract). The abnormal cells of Kaposi sarcoma cause...National Center for Advancing Translational Sciences
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Kaposi sarcoma (KS) is a low-grade vasoformative neoplasm associated with human herpesvirus-8 (HHV-8) or Kaposi sarcoma herpesvirus (KSHV) infection. Lesions frequently involve mucocutaneous sites, but may become more extensive to involve the lymph nodes and visceral organs. Skin lesions evolve from an early patch, to a plaque, and later...Athenahealth, Inc., 2019
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Kaposi sarcoma, rare and usually lethal cancer of the tissues beneath the surface of the skin or of the mucous membranes. The disease can spread to other organs, including the liver, lungs, and intestinal tract. Kaposi sarcoma is characterized by red-purple or blue-brown lesions of the skin, mucous...Encyclopedia Britannica, Inc., 2020
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