Cell
Langerhans' cell
Subclass of:
Dendritic Cells
Definitions related to langerhans cell:
  • Dendritic clear cells in the epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity.
    NCI
    U.S. National Cancer Institute, 2021
  • Cells of the immune system that work in the skin to fight infection.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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