Congenital Abnormality
Situs Inversus
Subclass of:
Congenital Abnormality
Etymology:
Latin situs = situation + inversus (from invertere = to turn in the opposite direction)
Definitions related to situs inversus:
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A congenital abnormality in which organs in the THORAX and the ABDOMEN are opposite to their normal positions (situs solitus) due to lateral transposition. Normally the STOMACH and SPLEEN are on the left, LIVER on the right, the three-lobed right lung is on the right, and the two-lobed left lung on the left. Situs inversus has a familial pattern and has been associated with a number of genes related to microtubule-associated proteins.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A congenital condition in which there is complete right-to-left reversal of the position of the major thoracic and abdominal organs (that is, they are arranged in a mirror image of the normal positioning).NCI ThesaurusU.S. National Cancer Institute, 2021
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Mirror-image transposition of the abdominal and/or thoracic viscera. (Makris S, Solomon HM, Clark R, Shiota K, Barbellion S, Buschmann J, Ema M, Fujiwara M, Grote K, Hazelden KP, Hew KW, Horimoto M, Ooshima Y, Parkinson M, Wise LD. Terminology of developmental abnormalities in common laboratory mammals (Version 2). Part B. Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):227-327.)CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(abdominal situs inversus) A left-right reversal (or mirror reflection") of the anatomical location of the viscera of the abdomen." [HPO:probinson]Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Situs inversus is a condition in which the arrangement of the internal organs is a mirror image of normal anatomy. It can occur alone (isolated, with no other abnormalities or conditions) or it can occur as part of a syndrome with various other defects. Congenital heart defects are present in about 5-10% of affected people. The...National Center for Advancing Translational Sciences
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