Pathologic Function
achlorhydria
a·chlor·hy·dri·a [ ay-klor-hy-dree-uh ]
Subclass of:
Acid-Base Imbalance;
Stomach Diseases
Etymology:
Greek a = not + chlorhydric = hydrochloric acid + -ia = condition
Definitions related to achlorhydria:
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A condition in which production of hydrochloric acid in the stomach is absent.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A condition in which the stomach produces little or no acid. This can affect digestion, cause stomach pain, and keep the body from absorbing vitamins and nutrients.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A lack of hydrochloric acid in the digestive juices in the stomach. Hydrochloric acid helps digest food.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Absence of hydrochloric acid in the gastric juice.NCI ThesaurusU.S. National Cancer Institute, 2021
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Lack of hydrochloric acid in gastric juice despite stimulation of gastric secretion.CRISP ThesaurusNational Institutes of Health, 2006
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Achlorhydria, in simple terms, means the absence of hydrochloric acid in gastric secretions and has been defined by multiple separate systems in reference to gastric acid secretion. First, achlorhydria has been defined by a peak acid output in response to a maximally effective stimulus that results in an intragastric pH greater than 5.WebMD, 2019
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Achlorhydria indicates the inability to produce gastric acid (i.e., hydrochloric acid ), even after stimulation with secretagogues (e.g., pentagastrin , histamine, betazole , or a meal). Serum gastrin is a marker for gastric acid output. A decrease in gastric acid interrupts a negative feedback pathway controlling gastrin secretion and...Athenahealth, Inc., 2019
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