Vitamin
alitretinoin
Brand Names:
Panretin
Effect:
Decreased Transcription to RNA
May Treat:
Sarcoma, Kaposi;
Skin Diseases
More Information:
Definitions related to alitretinoin:
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A retinoid that is used for the treatment of chronic hand ECZEMA unresponsive to topical CORTICOSTEROIDS. It is also used to treat cutaneous lesions associated with AIDS-related KAPOSI SARCOMA.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells.NCI ThesaurusU.S. National Cancer Institute, 2021
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(9-cis retinoic acid) A drug being studied for cancer prevention. It belongs to the family of drugs called retinoids.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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