Pharmacologic Substance
alprostadil Audio
[ al-pros-tuh-dil ]
Brand Names:
Caverject; Edex; Muse; Prostin VR
Effect:
Decreased Blood Pressure; Decreased Platelet Aggregation; Genitourinary Arterial Vasodilation; Venous Vasodilation
May Treat:
Aortic Arch Syndromes; Aortic Coarctation; Ductus Arteriosus, Patent; Hypertension, Pulmonary; Hypoplastic Left Heart Syndrome; Impotence, Vasculogenic; Pulmonary Valve Stenosis; Tetralogy of Fallot; Tricuspid Atresia
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to alprostadil:
  • (muse) Abbreviation for medicated urethral system for erection. In this therapy, a small drug pellet is inserted into the tip of the penis to produce an erection.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A drug that is used to treat impotence (inability to have an erection) and is being studied in the treatment of sexual problems in men who have had surgery for prostate cancer. It is a type of vasodilator.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A potent vasodilator agent that increases peripheral blood flow.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.