• Rapid swelling (edema) of the dermis, subcutaneous tissue, mucosa and submucosal tissues of the skin of the face, normally around the mouth, and the mucosa of the mouth and/or throat, as well as the tongue during a period of minutes to several hours. The swelling can also occur elsewhere, typically in the hands. Angioedema is similar to urticaria, but the swelling is subcutaneous rather than on the epidermis.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2021
• Rapid swelling of the deep layers of the skin due to transient vascular leakage of serous fluid.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Swelling involving the deep DERMIS, subcutaneous, or submucosal tissues, representing localized EDEMA. Angioedema often occurs in the face, lips, tongue, and larynx.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• Angioedema is edema of the deep dermis and subcutaneous tissues. It is usually an acute mast cell�mediated reaction caused by exposure to drug, venom, dietary, pollen, or animal dander allergens. Angioedema can also be an acute reaction to angiotensin-converting enzyme inhibitors, a chronic reaction, or a hereditary or an acquired...
  Merck Manuals
  Merck & Co., Inc., 2020
• Angioedema, first described in 1586, is usually defined by pronounced swelling of the deep dermis, subcutaneous or submucosal tissue, or mucous membranes as a result of vascular leakage. Other terms, such as giant urticaria, Quincke edema, and angioneurotic edema, have also been used in the past to describe this condition.
  Medscape
  WebMD, 2019
• Angioedema, allergic disorder in which large, localized, painless swellings similar to hives appear under the skin. The swelling is caused by massive accumulation of fluid (edema) following exposure to an allergen (a substance to which the person has been sensitized) or, in cases with a hereditary...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2020