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Cell
antigen-presenting cell Audio
[ an-tih-jen-preh-zen-ting sel ]
Subclass of:
Immune system; Cells
Definitions related to antigen-presenting cells:
  • (antigen presenting cell) A cell that enables a T-lymphocyte to recognize an antigen by engulfing the antigen, breaking down the antigen into smaller fragments which bind to MHC molecules on the surface of the antigen presenting cell. The T-lymphocyte can now recognize and bind with the MHC-linked antigen.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A type of immune cell that boosts immune responses by showing antigens on its surface to other cells of the immune system. An antigen-presenting cell is a type of phagocyte.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • (antigen presenting cell) Heterogeneous group of immunocompetent cells that mediates the cellular immune response by processing and presenting antigens to the T-cell receptor; traditional antigen presenting cells include macrophages, dendritic cells, Langerhans cells, and B-lymphocytes; follicular dendritic cells are also considered to be antigen presenting cells by some.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Specialized white blood cells that detect harmful substances in the body and then signal other immune system defenders (known as T-cells) to mount a defense.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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