Immunologic Factor
antinuclear autoantibody
Subclass of:
Autoantibodies
Definitions related to antibodies, antinuclear:
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(antinuclear antibody) A class of autoantibodies that are directed against structures within the nucleus of the cell. They can be associated with rheumatic disease, but may be present in unaffected individuals.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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(antinuclear antibody) An autoimmune antibody that is directed against structures within the nucleus of the cell.NCI ThesaurusU.S. National Cancer Institute, 2021
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Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(antinuclear autoantibody) Autoimmune, pathological antibodies against histones, DNA, nuclear RNA, or other components of the cell nucleus.CRISP ThesaurusNational Institutes of Health, 2006
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Antinuclear antibody (ANA) tests identify antibodies present in serum that bind to autoantigens present in the nuclei of mammalian cells. Most of these antibodies are IgG, but IgM and IgA have also been detected.WebMD, 2019
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