Biologically Active Substance
apelin
Subclass of:
Intercellular Signaling Peptides and Proteins
Definitions related to apelin:
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A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both APJ and CD4 ANTIGEN and is highly expressed in breast milk, where it may modulate the neonatal immune response.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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