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Related terms:
kinin
somatomedins
cytokine
endothelin
ephrins
adipokine
metastin
apelin
Biologically Active Substance
hedgehog proteins
hedge·hog pro·teins
Subclass of:
Intercellular Signaling Peptides and Proteins
Definitions related to hedgehog proteins:
  • (hedgehog family) A family of extracellular proteins that act as signaling molecules and regulate embryonic patterning events during development. They are synthesized as inactive precursors with an N-terminal signaling domain linked to a C-terminal autoprocessing domain, which has a structure that resembles intein protein splicing domains.
    NCI
    U.S. National Cancer Institute, 2021
  • A family of intercellular signaling proteins that play an important role in regulating the development of many TISSUES and organs. Their name derives from the observation of a hedgehog-like appearance in DROSOPHILA embryos with genetic mutations that block their action.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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