Disease or Syndrome
arthrogryposis
Subclass of:
Congenital musculoskeletal anomalies; Arthropathy; Myopathy
Etymology:
Greek arthron = joint + grypos = hooked + -osis = condition
Hence a persistent contraction of a joint.
Also called:
Multiple Congenital Contractures
Definitions related to arthrogryposis:
  • A rare, non-progressive congenital disorder characterized by multiple joint contractures which are present at birth.
    NCI
    U.S. National Cancer Institute, 2021
  • (arthrogryposis multiplex congenita) A group of disorders characterized by congenital limb contractures manifesting as limitation of movement of multiple limb joints at birth that is usually non-progressive and may include muscle weakness and fibrosis. This disorder is always associated with decreased intrauterine fetal movement which leads secondarily to the contractures.
    OrphaNet
    INSERM, 2021
  • Arthrogryposis multiplex congenita refers to a variety of conditions that involve congenital limitation of joint movement. Intelligence is typically normal except when the arthrogryposis is caused by a disorder or syndrome that also affects intelligence. Diagnosis is clinical. Treatment includes joint manipulation and casting and...
    Merck Manuals
    Merck & Co., Inc., 2025
  • Arthrogryposis, or arthrogryposis multiplex congenita (AMC), comprises nonprogressive conditions characterized by multiple joint contractures found throughout the body at birth. The term is currently used in connection with a very heterogeneous group of disorders that all include the common feature of multiple congenital joint...
    Medscape
    WebMD, 2025
  • Arthrogryposis multiplex congenita (AMC) refers to the development of multiple joint contractures affecting two or more areas of the body prior to birth. A contracture occurs when a joint becomes permanently fixed in a bent or straightened position, which can impact the function and range of motion of the joint and may lead to muscle...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.