Pharmacologic Substance
axitinib
[ ak-sih-tih-nib ]
Brand Names:
Inlyta
Effect:
Cellular Proliferation Alteration
May Treat:
Carcinoma, Renal Cell
More Information:
Definitions related to axitinib:
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A benzamide and indazole derivative that acts as a TYROSINE KINASE inhibitor of the VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR. It is used in the treatment of advanced RENAL CELL CARCINOMA.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called angiogenesis inhibitors and protein tyrosine kinase inhibitors.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect.NCI ThesaurusU.S. National Cancer Institute, 2021
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