Pharmacologic Substance
azauridine
Subclass of:
Aza Compounds; Uridine
Definitions related to azauridine:
  • A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • (6-azauridine) A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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