Pharmacologic Substance
betamethasone valerate
Effect:
Antipruritic Activity; Carbohydrate Metabolism Alteration; Decreased Cellular Migration; Decreased Glucocorticoid Secretion; Decreased Leukotriene Activity; Decreased Lysosomal Function; Decreased Prostaglandin Activity; Decreased Protein Synthesis; Decreased Thromboxane Activity; Lipid Metabolism Alteration
May Treat:
Dermatitis, Atopic;
Dermatitis, Seborrheic;
Facial Dermatoses;
Foot Dermatoses;
Hand Dermatoses;
Inflammation;
Leg Dermatoses;
Pruritus Ani;
Psoriasis;
Scalp Dermatoses
More Information:
Definitions related to betamethasone valerate:
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The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The 17-valerate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone valerate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.NCI ThesaurusU.S. National Cancer Institute, 2021
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