Neoplastic Process
breast carcinoma
breast car·ci·no·ma [ brest kahr-suh-noh-muh ]
Definitions related to breast carcinoma:
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(breast cancer) A malignant neoplasm that develops or arises in breast tissue.U.S. FDA GlossaryU.S. Food & Drug Administration, 2021
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(breast cancer) Breast cancer affects one in eight women during their lives. No one knows why some women get breast cancer, but there are many risk factors. Risks that you cannot change include Age - the risk rises as you get older; Genes - two genes, BRCA1 and BRCA2, greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested for the genes.; Personal factors - beginning periods before age 12 or going through menopause after age 55. Other risks include obesity, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35, and having dense breasts. Symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast, and discharge from a nipple. Breast self-exams and mammography can help find breast cancer early, when it is most treatable. One possible treatment is surgery. It could be a lumpectomy or a mastectomy. Other treatments include radiation therapy, chemotherapy, hormone therapy, and targeted therapy. Targeted therapy uses drugs or other substances that attack cancer cells with less harm to normal cells. Men can have breast cancer, too, but it is rare. NIH: National Cancer InstituteMedlinePlusU.S. National Library of Medicine, 2021
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(breast cancer) Cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla.NCI ThesaurusU.S. National Cancer Institute, 2021
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The presence of a carcinoma of the breast.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Breast cancer occurs when cells in the breast become abnormal and divide uncontrollably. Breast cancer usually starts in the glands that produce milk (lobules) or the tubes (ducts) that carry milk from the glands to the nipple.Merck & Co., Inc., 2020
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