Pharmacologic Substance
bromodeoxyuridine
Subclass of:
Deoxyuridine
Definitions related to bromodeoxyuridine:
  • (broxuridine) A drug that makes cancer cells more sensitive to radiation and is also used as a diagnostic agent to determine how fast cancer cells grow.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • (broxuridine) A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite; causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent; it has been given orphan drug status for use in the treatment of primary brain tumors.
    CRISP Thesaurus
    National Institutes of Health, 2006
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