Pharmacologic Substance
buserelin Audio
[ byoo-seh-reh-lin ]
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to buserelin:
  • A potent synthetic analog of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6, glycine10 deletion, and other modifications.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A synthetic analog of gonadotropin-releasing hormone (GnRH). Buserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids. Buserelin is more potent that GnRH. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An anticancer drug that belongs to the family of drugs called gonadotropin-releasing hormones. In prostate cancer therapy, buserelin blocks the production of testosterone in the testicles.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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