Pharmacologic Substance
carzelesin Audio
[ kar-zeh-leh-sin ]
Definitions related to carzelesin:
  • A cyclopropylpyrroloindole prodrug analogue and DNA minor groove binding agent, with antineoplastic activity. After hydrolysis, the cyclopropyl group of carzelesin alkylates N3-adenine in a sequence-selective fashion. This results in tumor growth inhibition.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An anticancer drug that belongs to the family of drugs called alkylating agents.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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