Research Activity
case-control studies
Subclass of:
Epidemiologic Studies
Definitions related to case-control studies:
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(case control) A study that compares groups of people with generally similar characteristics, those with the condition under study (case) and those without the condition under study (control).CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(case-control study) A research study that compares one group of people with a particular disease to a very similar group that does not have the same disease.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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(case-control study) A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls). Researchers study the medical and lifestyle histories of the people in each group to learn what factors may be associated with the disease or condition. For example, one group may have been exposed to a particular substance that the other was not. Also called retrospective study.NCI ThesaurusU.S. National Cancer Institute, 2021
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(case-control study) Retrospective study in which individuals with an outcome (cases) are compared with those who do not have the outcome (controls). The outcome variable (disease, event, experience, biomarker) is chosen first, and the exposure is evaluated in cases vs controls to see whether there is an association between exposure and outcome.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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Comparisons that start with the identification of persons with the disease or outcome of interest and a control (comparison, referent) group without the disease or outcome of interest. The relationship of an attribute is examined by comparing both groups with regard to the frequency or levels of outcome over time.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Case-control study, in epidemiology, observational (nonexperimental) study design used to ascertain information on differences in suspected exposures and outcomes between individuals with a disease of interest (cases) and comparable individuals who do not have the disease (controls). Analysis...Encyclopedia Britannica, Inc., 2020
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