Antibiotic
cefatrizine
Effect:
Decreased Cell Wall Synthesis & Repair
May Prevent:
Bacterial Infections
May Treat:
Bacterial Infections
Definitions related to cefatrizine:
  • A broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity. Cefatrizine binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Orally active semisynthetic cephalosporin antibiotic with broad-spectrum activity.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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