Antibiotic
cefepime
[ seh-feh-peem ]
Brand Names:
Maxipime
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Acinetobacter Infections;
Bacteroides Infections;
Bone Diseases, Infectious;
Escherichia coli Infections;
Fever;
Haemophilus Infections;
Klebsiella Infections;
Neutropenia;
Pneumonia, Bacterial;
Proteus Infections;
Pseudomonas Infections;
Pyelonephritis;
Sepsis;
Serratia Infections;
Skin Diseases, Bacterial;
Soft Tissue Infections;
Staphylococcal Infections;
Streptococcal Infections;
Urinary Tract Infections
More Information:
Definitions related to cefepime:
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A drug used to treat infection. It belongs to the family of drugs called cephalosporin antibiotics.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI ThesaurusU.S. National Cancer Institute, 2021
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