Antibiotic
cefoperazone
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Bone Diseases, Infectious;
Escherichia coli Infections;
Genital Diseases, Female;
Haemophilus Infections;
Klebsiella Infections;
Pneumonia, Bacterial;
Proteus Infections;
Pseudomonas Infections;
Salmonella Infections;
Serratia Infections;
Skin Diseases, Bacterial;
Soft Tissue Infections;
Staphylococcal Infections;
Streptococcal Infections;
Urinary Tract Infections
Definitions related to cefoperazone:
-
A semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI ThesaurusU.S. National Cancer Institute, 2021
-
Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> C
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.