Antibiotic
ceftibuten
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Bronchitis;
Escherichia coli Infections;
Haemophilus Infections;
Klebsiella Infections;
Moraxellaceae Infections;
Otitis Media;
Streptococcal Infections;
Tonsillitis
More Information:
Definitions related to ceftibuten:
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A cephalosporin antibacterial agent that is used in the treatment of infections, including urinary-tract and respiratory-tract infections.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI ThesaurusU.S. National Cancer Institute, 2021
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