Cell Function
cell senescence Audio
[ sel si-nes-uh-un s ]
Subclass of:
Cell physiology; Aging
Definitions related to cellular senescence:
  • A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
    Gene Ontology Dictionary
    Gene Ontology Consortium, 2021
  • Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (cell aging) Progression of the cell from its inception to the end of its lifespan.
    NCI
    U.S. National Cancer Institute, 2021
  • (cell senescence) Final stage of cellular differentiation, characterized by inability to grow, divide, or repair damaged cell components, leading to cell death.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • (cell senescence) The end stage in the life of a cell when the cell can no longer divide.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
    Gene Ontology Dictionary
    Gene Ontology Consortium, 2021
  • Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
    Gene Ontology Dictionary
    Gene Ontology Consortium, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.