Pharmacologic Substance
chlordiazepoxide Audio
chlor·di·az·e·pox·ide [ klawr-dahy-az-uh-pok-sahyd, klohr- ]
Brand Names:
Librax; Limbitrol
Effect:
Increased Central Nervous System GABA Activity
May Treat:
Alcohol Withdrawal Delirium; Anxiety Disorders
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to chlordiazepoxide:
  • A long-acting benzodiazepine with anxiolytic, sedative and hypnotic activity. Chlordiazepoxide exerts its effect by binding to the benzodiazepine site at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties; also used in the symptomatic treatment of alcohol withdrawal.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Chlordiazepoxide, tranquilizing drug used in the treatment of anxiety. The drug was introduced in the 1960s under several trade names, including Libritabs (the original base) and Librium (the hydrochloride salt). Chlordiazepoxide belongs to a group of chemically related compounds called...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.