Pharmacologic Substance
estazolam
Effect:
Increased Central Nervous System GABA Activity
May Treat:
Sleep Initiation and Maintenance Disorders
More Information:
Definitions related to estazolam:
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A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than DIAZEPAM or NITRAZEPAM.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A triazolo-benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system (CNS). This binding leads to an opening of the chloride channels, which allows the flow of chloride ions into the neuron, hyperpolarizes the neuronal membrane, inhibits neuronal firing, and leads to a decrease in neuronal excitability.NCI ThesaurusU.S. National Cancer Institute, 2021
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