Vitamin
cholecalciferol Audio
cho·le·cal·cif·er·ol [ koh-luh-kal-sif-uh-rawl, -rol, kol-uh- ]
Brand Names:
Animi-3 with Vitamin D; Calcet; Cal-Quick; Caltrate Gummy Bites; Caltrate Plus D; D3 Dots; Decalcitrol; Decara; Delta D3; Dialyvite Vitamin D3 Max; D-Vi-Sol; Encora AM Tablet; Encora PM Tablet; Folditam; Folgard OS; Fosamax Plus D; Infuvite; Infuvite Pediatric; Lactocal; Maximum D3; Multi-Delyn; MVC-Fluoride; Os-Cal 500 with D; Osteo-Poretical; Ostercal-D; Oysco 500 with D; Oysco D; Poly-Vi-Sol; Poly-Vi-Sol with Iron; ReliOn Glucose; Replesta NX; Thera-D; Tri-Vi-Sol; Viactiv Calcium Plus D; Vitafol-One; Vital E- A + D3; Vital E- Newborn; Vital E- Repro
Effect:
Decreased Renal Ca++ Excretion; Stimulation Small Intestine Fluid/Electrolyte Absorption
May Treat:
Cardiovascular Diseases; Crohn Disease; Familial Hypophosphatemic Rickets; Hypoparathyroidism; Kidney Failure, Chronic; Lung Neoplasms; Osteoporosis; Psoriasis; Skin Neoplasms
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to cholecalciferol:
  • (vitamin d3) Vitamin D synthesized from ergosterol in yeast and plants.
    CRCH Nutrition Terminology
    Cancer Research Center of Hawaii, University of Hawaii, 2021
  • A nutrient that the body needs in small amounts to function and stay healthy. Cholecalciferol helps the body use calcium and phosphorus to make strong bones and teeth. It is fat-soluble (can dissolve in fats and oils) and is found in fatty fish, egg yolks, and dairy products. Skin exposed to sunshine can also make cholecalciferol. Not enough cholecalciferol can cause a bone disease called rickets. It is being studied in the prevention and treatment of some types of cancer.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption.
    NCI
    U.S. National Cancer Institute, 2021
  • Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Produced in human and other animal tissue by photoactivation (normally sunlight on skin) of 7-dehydrocholesterol.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.